Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound Lines, Inc. + FlixBus | Bus | Ann Arbor | Gateway Station | Cheapest | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Ann Arbor | Gateway Station | Fastest |
Last refresh of the prices: Yesterday at 11:25 PM EST.
Compare 2 ways to go from Ann Arbor to St. Louis
Among the sustainable travel choices, the train stands out as a good way to reach St. Louis. The journey takes about 12 hours 53 minutes, and with fares starting at just $109, it presents an excellent value for a comfortable ride.
Where are the popular stops in Ann Arbor and St. Louis?
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Frequently asked questions about travelling from Ann Arbor to St. Louis by bus
What is the distance between Ann Arbor and St. Louis?
It's about 682 km (423 miles) from Ann Arbor to St. Louis.
What are the departure and arrival locations for buses traveling from Ann Arbor to St. Louis?
Buses departing from Train Station in Ann Arbor will take you to Gateway Station in St. Louis.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Ann Arbor to St. Louis was searched and found on Nov 29, 2025 with a price of $142To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Ann Arbor to St. Louis, as early as possible.
You can expect to pay from $142 to $303 for a bus ticket from Ann Arbor to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at $142 which is on 2025-11-29.
What's the cheapest way to go from Ann Arbor to St. Louis?
The bus is the cheapest travel choice for this destination
