What is the distance between Ann Arbor and St. Louis?

Ann Arbor and St. Louis are 423 miles (682 km) apart.

What are the departure and arrival stations when taking the bus from Ann Arbor to St. Louis?

Buses going from Ann Arbor to St. Louis begin their journey at Train Station and reach their destination at Gateway Station.

What are the best sights and things to do in St. Louis?

Once in St. Louis, you can start exploring the city and discover its surroundings. The top sights and things to do are Saint Louis Science Center, St. Louis Cardinals, Powell Symphony Hall, Saint Louis Zoo and Old St. Louis County Courthouse.

Bus Ann Arbor to St. Louis from $78 | Refundable Tickets

Next bus departures

Next departures for Ann Arbor to St. Louis on November 25
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
Greyhound Lines, Inc. + FlixBus	Bus	9:20am	Ann Arbor	14h 50m	11:10pm	Gateway Station	Cheapest
Greyhound Lines, Inc. + FlixBus	Bus	5:20pm	Ann Arbor	14h 5m	6:25am	Gateway Station	Fastest

Last refresh of the prices: Yesterday at 11:25 PM EST.

Compare 2 ways to go from Ann Arbor to St. Louis

We recommend taking the train

Among the sustainable travel choices, the train stands out as the good way to reach St. Louis. The journey takes about 12 hours 53 minutes and with fares starting at just $75, it presents an excellent value for a comfortable ride.

1train per day

12h 53mAverage Duration

423 milesDistance

62kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$78 - $245	Average Duration14h 50m	CO₂ emissions 17kg CO₂e
Train	Average Price$75 - $506	Average Duration12h 53m	CO₂ emissions 62kg CO₂e

Where are the popular stops in Ann Arbor and St. Louis?

Stops in Ann Arbor

A
Train Station
325 Depot St, Ann Arbor, MI 48104, USA
Visit page

Stops in St. Louis

A
Gateway Station
430 S 15th St, St Louis, MO 63103
Visit page

Compare bus companies

Greyhound

3.5/587,394 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

FlixBus

3.5/511,440 reviews

Staff4.1

Timeliness3.9

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

US bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Frequently asked questions about traveling from Ann Arbor to St. Louis by bus

What is the distance between Ann Arbor and St. Louis?
What are the departure and arrival stations when taking the bus from Ann Arbor to St. Louis?
What are the best sights and things to do in St. Louis?

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11/23

No data

11/24

$135

Today

$209

11/26

$116

11/27

No data

11/28

No data

11/29

$98

11/30

$134

The cheapest trip from Ann Arbor to St. Louis was searched and found on Nov 29, 2025 with a price of $98

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Ann Arbor to St. Louis, as early as possible.

You can expect to pay from $98 to $209 for a bus ticket from Ann Arbor to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at $98 which is on 2025-11-29.