Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound Lines, Inc. + FlixBus | Bus | Ann Arbor | Gateway Station | CheapestFastest | ||||
 | Bus | Ann Arbor | Gateway Station | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Ann Arbor | Gateway Station | No tags |
Last refresh of the prices: Last Tuesday at 12:43 PM EST.
Compare 2 ways to go from Ann Arbor to St. Louis
Among the sustainable travel choices, the Train stands out as the good way to reach St. Louis. The journey takes about 13 hours and with fares starting at just $88, it presents an excellent value for a comfortable ride.
Where are the popular stops in Ann Arbor and St. Louis?
Compare bus companies
Frequently asked questions about traveling from Ann Arbor to St. Louis by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Ann Arbor to St. Louis?
The cheapest bus tickets from Ann Arbor to St. Louis start from $82. The average price for this route is around $147. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Ann Arbor to St. Louis?
The average bus trip duration from Ann Arbor to St. Louis is 14h 50m, covering a distance of 423 miles (682 km). The quickest bus can get you there in 11h 25m and is operated by FlixBus.
Which bus companies service the Ann Arbor to St. Louis route?
What is the earliest and latest departure time for the bus from Ann Arbor to St. Louis?
The earliest bus departs from Ann Arbor to St. Louis at 12:35am. And the latest bus departs at 7:45pm.
What are the CO₂ emissions for the bus trip from Ann Arbor to St. Louis?
A bus trip from Ann Arbor to St. Louis generates an estimated 17 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Ann Arbor to St. Louis?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87500 reviews.
Which bus company has the best Wi-Fi from Ann Arbor to St. Louis?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company has the most timely service from Ann Arbor to St. Louis?
According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Ann Arbor to St. Louis?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Ann Arbor to St. Louis was searched and found on Jan 16, 2026 with a price of $86To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Ann Arbor to St. Louis, as early as possible.
You can expect to pay from $86 to $121 for a bus ticket from Ann Arbor to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at $93 which is on 2026-01-21.
What's the cheapest way to go from Ann Arbor to St. Louis?
The Bus is the cheapest travel choice for this destination
