Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound Lines, Inc. | Bus | Brookline | UCSD Health La Jolla Station | Cheapest | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Boston (South Station) | UCSD Health La Jolla Station | Fastest | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Boston (South Station) | San Diego (Old Town-FlixBus) | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Boston (South Station) | Downtown SD (Seaport) | No tags | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Brookline | San Diego (Old Town-FlixBus) | No tags |
Last refresh of the prices: Last Wednesday at 12:56 AM EST.
Compare 2 ways to go from Boston to San Diego
Among the sustainable travel choices, the bus stands out as a good way to reach San Diego. The journey takes about 3 days, 11 hours 10 minutes, and with fares starting at just $203, it presents an excellent value for a comfortable ride.
Where are the popular stops in Boston and San Diego?
Stops in Boston
- A145 Dartmouth St, Boston, MA 02116, USA
- B100 Legends Way, Boston, MA 02114, USA
- C
Copley Square
115-127 St James Ave, Boston, MA 02116, USA - D
Prudential MBTA Station
220 Huntington Ave, Boston, MA 02115, USA - E
Copley MBTA Station
650 Boylston St, Boston, MA 02116, USA - F
Long Wharf
66 Long Wharf, Boston, MA 02110, USA
Stops in San Diego
- A
Mission Valley Sheraton
1433 Camino del Rio S, San Diego, CA 92108, USA - B
Old Town Courtyard Marriot
2435 Jefferson St, San Diego, CA 92110, USA - C
Downtown Holiday Inn
1617 1st Ave, San Diego, CA 92101, USA - D
Greyhound Station
1313 National Ave, San Diego, CA 92101, USA - E
Market St. & Park Blvd
601 Park Boulevard, San Diego, CA 92101, USA - F
San Ysidro McDonald's
727 E San Ysidro Blvd, San Diego, CA 92173, USA
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Frequently asked questions about travelling from Boston, MA, US to San Diego, CA, US by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Boston to San Diego?
The cheapest bus tickets from Boston to San Diego start from $203. The average price for this route is around $706. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Boston to San Diego?
The average bus travel time from Boston to San Diego is 3d 11h, covering a distance of 4147 km. The quickest bus can get you there in 3d 1h and is operated by Greyhound.
Which bus companies service the Boston to San Diego route?
What are the earliest and latest departure times for the bus from Boston to San Diego?
The earliest bus departs from Boston to San Diego at 1:30am. And the latest bus departs at 8:55pm.
What are the CO₂ emissions for the bus trip from Boston to San Diego?
A bus trip from Boston to San Diego generates an estimated 104 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Boston to San Diego?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87387 reviews.
Which bus company has the best Wi-Fi from Boston to San Diego?
Based on Busbud reviews, the bus company FlixBus has the highest Wi-Fi rating with a score of 2.7.
Which bus company has the best on-time performance from Boston to San Diego?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Boston to San Diego?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Boston, MA, US to San Diego, CA, US was searched and found on Dec 6, 2025 with a price of $480To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Boston, MA, US to San Diego, CA, US, as early as possible.
You can expect to pay from $480 to $893 for a bus ticket from Boston, MA, US to San Diego, CA, US based on the last 2 days. You can expect to find the cheapest price for the trip at $480 which is on 2025-12-06.
What's the cheapest way to go from Boston, MA, US to San Diego, CA, US?
The bus is the cheapest travel choice for this destination
