Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound Lines, Inc. | Bus | Niagara Frontier Transportation Authority | City of Portland | Cheapest | ||||
 | Bus | Niagara Frontier Transportation Authority | City of Portland | Fastest | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Buffalo (BUF) Airport | City of Portland | No tags |
Last refresh of the prices: Yesterday at 7:00 PM EST.
Get from Buffalo to Portland
The journey takes about 20 hours 51 minutes, and with fares starting at just $160, it presents an excellent value for a comfortable ride.
Where are the popular stops in Buffalo and Portland?
Stops in Buffalo
- B185 Ellicott St, Buffalo, NY 14203, USA
- C75 Exchange St, Buffalo, NY 14203, USA
Stops in Portland
- A
Greyhound Station Portland Maine
389 Congress St, Portland, ME 04102, USA
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Frequently asked questions about travelling from Buffalo, NY to Portland, ME by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Buffalo to Portland?
The cheapest bus tickets from Buffalo to Portland start from $160. The average price for this route is around $160. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Buffalo to Portland?
The average bus travel time from Buffalo to Portland is 20h 51m, covering a distance of 701 km. The quickest bus can get you there in 19h 55m and is operated by Greyhound.
Which bus companies service the Buffalo to Portland route?
What are the earliest and latest departure times for the bus from Buffalo to Portland?
The earliest bus departs from Buffalo to Portland at 12:55am. And the latest bus departs at 11:59pm.
What are the CO₂ emissions for the bus trip from Buffalo to Portland?
A bus trip from Buffalo to Portland generates an estimated 18 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Buffalo to Portland?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87387 reviews.
Which bus company has the best Wi-Fi from Buffalo to Portland?
Based on Busbud reviews, the bus company FlixBus has the highest Wi-Fi rating with a score of 2.7.
Which bus company has the best on-time performance from Buffalo to Portland?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Buffalo to Portland?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Buffalo, NY to Portland, ME was searched and found on Nov 28, 2025 with a price of $298To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Buffalo, NY to Portland, ME, as early as possible.
You can expect to pay from $298 to $325 for a bus ticket from Buffalo, NY to Portland, ME based on the last 2 days. You can expect to find the cheapest price for the trip at $298 which is on 2025-11-28.
