Cheap buses leaving Wednesday
One passenger / one way
- This trip is recommended because it is the: Cheapest
- This trip is recommended because it is the: Fastest
- Departure time: August 6 atDeparture city: CharlestonDeparture location: 4565 Gaynor Ave, North CharlestonArrival time: August 7 atDestination city: HarrisburgDestination location: HarrisburgOperated by: FlixBus
Vehicle: BusDuration:
Last refresh of the prices: Last Wednesday at 10:51 AM EDT.
Prices and availability are subject to change.
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Compare 2 ways to go from Charleston to Harrisburg
Busbud recommends taking the bus from Charleston to HarrisburgAmong the sustainable travel choices, the bus stands out as a good way to reach Harrisburg. The journey takes about 23 hours 40 minutes, and with fares starting at just US$88, it presents an excellent value for a comfortable ride.
Bus Charleston, SC, US to Harrisburg: Trip Overview
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Charleston to Harrisburg Bus
With Busbud, comparing and booking tickets for a bus from Charleston to Harrisburg is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.
Bus service from Charleston to Harrisburg will be provided by the most trusted bus companies.
Whether it is cheap bus tickets or more luxurious buses going to Harrisburg from Charleston, we help you find what you're looking for based on how much of a budget you have.
Where are the popular stops in Charleston and Harrisburg?
Frequently asked questions on the trip Charleston, SC, US - Harrisburg
What is the distance between Charleston and Harrisburg?
It's about 878 km (544 miles) from Charleston to Harrisburg.
What are the departure and arrival locations for buses traveling from Charleston to Harrisburg?
Buses traveling this route start their trip at Charleston Bus Station, in Charleston, and end it at Harrisburg Bieber Greyhound Station, in Harrisburg.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Charleston, SC, US to Harrisburg was searched and found on Aug 6, 2025 with a price of US$104To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Charleston, SC, US to Harrisburg, as early as possible.
You can expect to pay from US$104 to US$184 for a bus ticket from Charleston, SC, US to Harrisburg based on the last 2 days. You can expect to find the cheapest price for the trip at US$104 which is on 2025-08-06.
About Bus Travel
Bus Travel Tips
Meet and talk to locals at the bus stations while travelling from Charleston to Harrisburg.There is no better way to get inside travel information while exploring a new city than to go straight to its people.
Much more than a mere vehicle taking you from Charleston to Harrisburg, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.
Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Charleston to Harrisburg.
Make a music playlist for your bus ride from Charleston to Harrisburg, and enjoy the scenery to tunes from your own personal soundtrack.
Did you know?
The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.
The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.
Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!
What's the cheapest way to go from Charleston, SC, US to Harrisburg?
The bus is the cheapest travel choice for this destinationTop travelled bus routes
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