Bus Tickets from Charleston, WV, US to St. Louis

Previously seen trips

Next departures for Charleston to St. Louis on October 13
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound
Charleston Bus Station
Gateway StationNo tags
Greyhound
Charleston Bus Station
Gateway StationNo tags
Greyhound
Charleston Bus Station
Gateway StationNo tags
Greyhound
Charleston Bus Station
Gateway StationNo tags
Greyhound
Charleston Bus Station
Gateway StationNo tags

Accepted payments

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Compare 2 ways to go from Charleston to St. Louis

Bus
Average PriceUS$69 - US$164Average Duration15h 10m
19kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average PriceUS$226 - US$277Average Duration23h 38m
68kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Charleston to St. Louis

Among the sustainable travel choices, the bus stands out as a good way to reach St. Louis. The journey takes about 15 hours 10 minutes, and with fares starting at just US$69, it presents an excellent value for a comfortable ride.

1bus per day
15h 10mAverage Duration
US$69Cheapest ticket
19kgCO₂ emissions

Bus Charleston, WV, US to St. Louis: Trip Overview

Average Ticket PriceUS$78
Average Bus Trip Duration15h 10m
Number of daily buses1
Earliest bus departure9:15am
Distance746 km
Latest bus departure9:20am

Charleston to St. Louis Bus

With Busbud, comparing and booking tickets for a bus from Charleston to St. Louis is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make sure you can find a bus service from Charleston to St. Louis from the most reliable bus companies operating this trip.

Whether it is cheap bus tickets or more luxurious buses going to St. Louis from Charleston, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Charleston, WV, US - St. Louis

  1. What is the travel distance from Charleston to St. Louis?

    The distance covered from Charleston to St. Louis is 747 km (464 miles).

  2. What are the departure and arrival locations for buses traveling from Charleston to St. Louis?

    Buses traveling this route start their trip at Charleston Greyhound Bus Station, in Charleston, and end it at Gateway Station, in St. Louis.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
10-10
US$196
10-11
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Today
US$166
10-13
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10-14
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10-15
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10-16
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10-17
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busbud logoThe cheapest trip from Charleston, WV, US to St. Louis was searched and found on Oct 12, 2025 with a price of US$166

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Charleston, WV, US to St. Louis, as early as possible.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Charleston to St. Louis.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Charleston to St. Louis, get comfy and count the stars.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Charleston to St. Louis.

Tune out to the fine sounds of your best music playlist on your bus trip from Charleston to St. Louis while indulging in miles on end of beautiful scenic views.

Did you know?

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

What's the cheapest way to go from Charleston, WV, US to St. Louis?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Charleston, WV, US by bus?

Bus from St. Louis to Charleston, WV, US

You can also go to St. Louis by train

Train from Charleston, WV, US to St. Louis

Why choose Busbud?

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