Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Cleveland Bus Station | Des Moines | Cheapest | ||||
| Bus | Cleveland Bus Station | Des Moines | Fastest | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Cleveland Bus Station | Des Moines | No tags |
Last refresh of the prices: Today at 11:22 AM EST.
Get from Cleveland to Des Moines
The journey takes about 1 day, 2 hours 55 minutes, and with fares starting at just $227, it presents an excellent value for a comfortable ride.
Where are the popular stops in Cleveland and Des Moines?
Stops in Cleveland
- A
Greyhound Station
1465 Chester Ave, Cleveland, OH 44114, USA
Stops in Des Moines
- A
Jefferson/Trailways Depot
1501 2nd Ave North, Des Moines, IA 50314 - B
1514 East Grand Ave
1514 East Grand Avenue,, Des Moins, IA, 50316
Compare bus companies
Based on 87471 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. Greyhound ticket prices on this trip start at $227
Frequently asked questions about travelling from Cleveland, OH, US to Des Moines by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Cleveland to Des Moines?
The cheapest bus tickets from Cleveland to Des Moines start from $227. The average price for this route is around $269. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Cleveland to Des Moines?
The average bus travel time from Cleveland to Des Moines is 1d 2h, covering a distance of 991 km. The quickest bus can get you there in 16h and is operated by Greyhound.
Which bus companies service the Cleveland to Des Moines route?
Several major bus companies operate on this route with 3 buses available per day.
What are the earliest and latest departure times for the bus from Cleveland to Des Moines?
The earliest bus departs from Cleveland to Des Moines at 3:35am. And the latest bus departs at 4:40pm.
What are the CO₂ emissions for the bus trip from Cleveland to Des Moines?
A bus trip from Cleveland to Des Moines generates an estimated 25 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Cleveland, OH, US to Des Moines was searched and found on Jan 2, 2026 with a price of $261To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Cleveland, OH, US to Des Moines, as early as possible.
You can expect to pay from $261 to $265 for a bus ticket from Cleveland, OH, US to Des Moines based on the last 0 days. You can expect to find the cheapest price for the trip at $261 which is on 2026-01-02.
