Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Columbus Bus Station | Winston Salem Greyhound Bus Station | No tags | ||||
| Bus | Columbus Bus Station | Winston Salem Greyhound Bus Station | No tags | ||||
| Bus | Columbus (E Mound St) | Winston Salem Greyhound Bus Station | No tags | ||||
| Bus | Columbus (E Mound St) | Winston Salem Greyhound Bus Station | No tags | ||||
| Bus | Columbus (E Mound St) | Winston Salem Greyhound Bus Station | No tags |
Get from Columbus to Winston-Salem
The journey takes about 9 hours 25 minutes, and with fares starting at just $122, it presents an excellent value for a comfortable ride.
Where are the popular stops in Columbus and Winston-Salem?
Stops in Columbus
- A
Columbus Bus Station
25 E Rich St, Columbus, OH 43205, USA
Stops in Winston-Salem
- A
Winston Salem Greyhound Bus Station
100 W 5th St, Winston Salem, NC 27101 - B
E Sprague St
841 E Sprague St, Winston-Salem, NC 27107, USA - C
Winston-Salem Bus Stop
2500 Old Lexington Rd, Winston-Salem, NC 27107, USA - D
1237 Silas Creek Pkwy
1237 Silas Creek Pkwy., Winston-Salem, NC 27127 (Hong Kong King Buffet)
Compare bus companies
Based on 87442 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. Greyhound ticket prices on this trip start at $122
Frequently asked questions about travelling from Columbus, OH to Winston-Salem by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Columbus to Winston-Salem?
The cheapest bus tickets from Columbus to Winston-Salem start from $122. The average price for this route is around $172. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Columbus to Winston-Salem?
The average bus travel time from Columbus to Winston-Salem is 9h 25m, covering a distance of 492 km. The quickest bus can get you there in 9h 25m and is operated by Greyhound.
Which bus companies service the Columbus to Winston-Salem route?
Several major bus companies operate on this route with 2 buses available per day.
What are the earliest and latest departure times for the bus from Columbus to Winston-Salem?
The earliest bus departs from Columbus to Winston-Salem at 12:50am. And the latest bus departs at 9:10pm.
What are the CO₂ emissions for the bus trip from Columbus to Winston-Salem?
A bus trip from Columbus to Winston-Salem generates an estimated 12 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Columbus, OH to Winston-Salem was searched and found on Dec 24, 2025 with a price of $99To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Columbus, OH to Winston-Salem, as early as possible.
You can expect to pay from $99 to $155 for a bus ticket from Columbus, OH to Winston-Salem based on the last 2 days. You can expect to find the cheapest price for the trip at $99 which is on 2025-12-24.
