Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound + FlixBus | Bus | Des Moines (Subway) | Columbus (E Mound St) | No tags | ||||
FlixBus + Greyhound | Bus | Des Moines (Subway) | 100 E Rich St | No tags | ||||
Greyhound + FlixBus | Bus | Des Moines (Subway) | Columbus (Ohio State University) | No tags | ||||
 | Bus | Des Moines (Subway) | Columbus (E Mound St) | No tags | ||||
Greyhound + FlixBus | Bus | Des Moines (Subway) | 100 E Rich St | No tags |
Get from Des Moines to Columbus
The journey takes about 18 hours 5 minutes, and with fares starting at just $123, it presents an excellent value for a comfortable ride.
Where are the popular stops in Des Moines and Columbus?
Stops in Des Moines
- A
Jefferson/Trailways Depot
1501 2nd Ave North, Des Moines, IA 50314 - B
1514 East Grand Ave
1514 East Grand Avenue,, Des Moins, IA, 50316
Stops in Columbus
- A
Columbus Bus Station
25 E Rich St, Columbus, OH 43205, USA
Compare bus companies
Based on 87534 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi‑Fi. Greyhound ticket prices on this trip start at $123
Frequently asked questions about travelling from Des Moines to Columbus, OH by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Des Moines to Columbus?
The cheapest bus tickets from Des Moines to Columbus start from $123. The average price for this route is around $150. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Des Moines to Columbus?
The average bus travel time from Des Moines to Columbus is 18h 5m, covering a distance of 911 km. The quickest bus can get you there in 18h 5m and is operated by Greyhound.
Which bus companies service the Des Moines to Columbus route?
Several major bus companies operate on this route with 3 buses available per day.
What are the earliest and latest departure times for the bus from Des Moines to Columbus?
The earliest bus departs from Des Moines to Columbus at 5:30am. And the latest bus departs at 4:20pm.
What are the CO₂ emissions for the bus trip from Des Moines to Columbus?
A bus trip from Des Moines to Columbus generates an estimated 22.774025 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Des Moines to Columbus, OH was searched and found on Apr 13, 2026 with a price of $128To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Des Moines to Columbus, OH, as early as possible.
You can expect to pay from $128 to $148 for a bus ticket from Des Moines to Columbus, OH based on the last 2 days. You can expect to find the cheapest price for the trip at $135 which is on 2026-04-14.
