Bus Tickets from Des Moines to Columbus, OH

Next departures

Next departures for Des Moines to Columbus on October 28
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc.
Des Moines
Columbus (E Mound St)Cheapest
Greyhound Lines, Inc. + FlixBus
Des Moines
100 E Rich StFastest
Greyhound Lines, Inc. + FlixBus
Des Moines
Columbus (E Mound St)No tags

Last refresh of the prices: Today at 3:24 PM CDT.

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Get from Des Moines to Columbus

busbud logoThis route is served by bus only

The journey takes about 18 hours 5 minutes, and with fares starting at just US$129, it presents an excellent value for a comfortable ride.

3bus per day
18h 5mAverage Duration
911 kmDistance
23kgCO₂ emissions

Bus Des Moines to Columbus, OH: Trip Overview

Average Ticket PriceUS$147
Average Bus Trip Duration18h 5m
Number of daily buses3
Earliest bus departure5:30am
Distance911 km
Latest bus departure9:30am

Des Moines to Columbus Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Des Moines to Columbus.

Bus service from Des Moines to Columbus will be provided by the most trusted bus companies.

Discover how much the bus trip from Des Moines to Columbus will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Des Moines - Columbus, OH

  1. What is the distance between Des Moines and Columbus?

    The distance covered from Des Moines to Columbus is 913 km (566 miles).

  2. What are the departure and arrival locations for buses traveling from Des Moines to Columbus?

    Buses traveling this route start their trip at Jefferson/Trailways Depot, in Des Moines, and end it at Columbus Bus Station, in Columbus.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
10-25
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10-26
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Today
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10-28
US$121
10-29
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10-30
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10-31
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11-01
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busbud logoThe cheapest trip from Des Moines to Columbus, OH was searched and found on Oct 28, 2025 with a price of US$121

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Des Moines to Columbus, OH, as early as possible.

You can expect to pay from US$121 to US$121 for a bus ticket from Des Moines to Columbus, OH based on the last 2 days. You can expect to find the cheapest price for the trip at US$121 which is on 2025-10-28.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Des Moines to Columbus but it'll also be endearing to native speakers who will surely appreciate your effort.

Much more than a mere vehicle taking you from Des Moines to Columbus, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Des Moines to Columbus will emit less CO2 than a car or an airplane.

Tune out to the fine sounds of your best music playlist on your bus trip from Des Moines to Columbus while indulging in miles on end of beautiful scenic views.

Did you know?

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Will you be returning to Des Moines by bus?

Bus from Columbus, OH to Des Moines

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