Bus Tickets from Des Moines to Columbus, OH

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TodayJul 17
TomorrowJul 18
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from $129
MonJul 21
TueJul 22
from $129
WedJul 23
from $128
ThuJul 24

Cheap buses leaving Sunday

One passenger / one way

  • This trip is recommended because it is: Cheapest + Fastest
    Departure time: July 20 at
    Departure city: Des Moines
    Departure location: Des Moines (Subway)
    Arrival time: July 21 at
    Destination city: Columbus
    Destination location: Columbus (E Mound St)
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: July 20 at
    Departure city: Des Moines
    Departure location: Des Moines (Subway)
    Arrival time: July 21 at
    Destination city: Columbus
    Destination location: 100 E Rich St
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:

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Bus Des Moines to Columbus: Trip Overview

Average ticket price$131
Average bus trip duration18h 5m
Number of daily buses2
Earliest bus departure5:30am
Distance565 miles (911 km)

Des Moines to Columbus Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Des Moines to Columbus.

Bus service from Des Moines to Columbus will be provided by the most trusted bus companies.

Discover how much the bus trip from Des Moines to Columbus will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions for your trip Des Moines - Columbus, OH

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
07/15
$130
07/16
No data
Today
No data
07/18
No data
07/19
No data
07/20
$121
07/21
No data
07/22
$121
busbud logoThe cheapest trip from Des Moines to Columbus was searched and found on Jul 20, 2025 with a price of $121

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Des Moines to Columbus, as early as possible.

You can expect to pay from $121 to $130 for a bus ticket from Des Moines to Columbus based on the last 2 days. You can expect to find the cheapest price for the trip at $121 which is on 2025-07-20.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Des Moines to Columbus but it'll also be endearing to native speakers who will surely appreciate your effort.

Much more than a mere vehicle taking you from Des Moines to Columbus, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Des Moines to Columbus will emit less CO2 than a car or an airplane.

Tune out to the fine sounds of your best music playlist on your bus trip from Des Moines to Columbus while indulging in miles on end of beautiful scenic views.

Did you know?

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Will you be returning to Des Moines by bus?

Bus from Des Moines to Columbus

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