Bus Tickets from Des Moines to Harrisburg

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Bus Des Moines to Harrisburg: Trip Overview

Average Ticket PriceUS$174
Average Bus Trip Duration1d 3h
Number of daily buses1
Earliest bus departure5:30am
Distance1410 km

Des Moines to Harrisburg Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Des Moines to Harrisburg.

We make it our job to connect you with the most dependable bus companies that cover bus service from Des Moines to Harrisburg.

Whether it is cheap bus tickets or more luxurious buses going to Harrisburg from Des Moines, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Des Moines - Harrisburg

  1. How long is the bus ride from Des Moines to Harrisburg?

    The bus ride from Des Moines to Harrisburg takes 1d 3h, on average. For the shortest travel time, select the fastest bus available, which will take you to Harrisburg in about 1d 3h.

  2. How far is Des Moines from Harrisburg?

    The distance between Des Moines and Harrisburg is approximately 1412 km (876 miles).

  3. What are the departure and arrival locations for buses traveling from Des Moines to Harrisburg?

    Buses departing from Jefferson/Trailways Depot in Des Moines will take you to Harrisburg Bieber Greyhound Station in Harrisburg.

  4. What is the cheapest way to travel from Des Moines to Harrisburg?

    Taking the bus is the most budget-friendly option to travel from Des Moines to Harrisburg. Starting at US$172, this bus is the most cost-effective option for your journey.

  5. How much does it cost to take the bus from Des Moines to Harrisburg?

    You can expect to pay around US$174 for the bus ride from Des Moines to Harrisburg.

  6. Can I take an overnight bus from Des Moines to Harrisburg?

    Yes! If you're heading from Des Moines to Harrisburg, you'll find buses departing until 5:30am and arriving the next day.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

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US$167
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busbud logoThe cheapest trip from Des Moines to Harrisburg was searched and found on Jun 4, 2025 with a price of US$167

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Des Moines to Harrisburg, as early as possible.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Des Moines to Harrisburg but it'll also be endearing to native speakers who will surely appreciate your effort.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Des Moines to Harrisburg.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Des Moines to Harrisburg.

Make a music playlist for your bus ride from Des Moines to Harrisburg, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

Will you be returning to Des Moines by bus?

Bus from Des Moines to Harrisburg

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