Bus Tickets from Durham, NC, US to Chicago

Previously seen trips

Next departures for Durham to Chicago on October 31
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus + Greyhound
Durham Greyhound Bus Station
Chicago 95Th & Dan RyanNo tags
Greyhound
Durham Greyhound Bus Station
Downtown Greyhound StationNo tags
Greyhound
Durham Greyhound Bus Station
Chicago 95Th & Dan RyanNo tags
Greyhound + FlixBus
Durham Greyhound Bus Station
537-517 W. Jackson BlvdNo tags
Greyhound + FlixBus
Durham Greyhound Bus Station
Downtown Greyhound StationNo tags

Accepted payments

  • Visa
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  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Compare 2 ways to go from Durham to Chicago

busbud logoWe recommend taking the bus

Among the sustainable travel choices, the bus stands out as a good way to reach Chicago. The journey takes about 1 day, 2 hours 5 minutes, and with fares starting at just US$101, it presents an excellent value for a comfortable ride.

13bus per day
1d 2hAverage Duration
987 kmDistance
25kgCO₂ emissions
Bus
Average PriceUS$101 - US$427Average Duration1d 2h
25kg CO₂e
Train
Average PriceUS$198 - US$1,958Average Duration1d 15h
91kg CO₂e

Bus Durham, NC, US to Chicago: Trip Overview

Average Ticket PriceUS$188
Average Bus Trip Duration1d 2h
Number of daily buses13
Earliest bus departure1:10am
Distance987 km
Latest bus departure10:05pm

Durham to Chicago Bus

With Busbud, comparing and booking tickets for a bus from Durham to Chicago is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make it our job to connect you with the most dependable bus companies that cover bus service from Durham to Chicago.

From cheap bus tickets to more luxurious buses travelling from Durham to Chicago, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Durham, NC, US - Chicago

  1. How far is Durham from Chicago?

    The distance between Durham and Chicago is around 999 km (620 miles).

  2. What are the departure and arrival locations for buses traveling from Durham to Chicago?

    Buses traveling this route start their trip at Durham Greyhound Bus Station, in Durham, and end it at Downtown Greyhound Station, in Chicago.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
10-29
US$147
10-30
US$184
Today
US$115
11-01
No data
11-02
No data
11-03
No data
11-04
No data
11-05
No data
busbud logoThe cheapest trip from Durham, NC, US to Chicago was searched and found on Oct 31, 2025 with a price of US$115

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Durham, NC, US to Chicago, as early as possible.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Durham to Chicago.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Durham to Chicago.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Durham to Chicago that are otherwise impossible to come by with a plane.

Tune out to the fine sounds of your best music playlist on your bus trip from Durham to Chicago while indulging in miles on end of beautiful scenic views.

Did you know?

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

What's the cheapest way to go from Durham, NC, US to Chicago?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Durham, NC, US by bus?

Bus from Chicago to Durham, NC, US

You can also go to Chicago by train

Train from Durham, NC, US to Chicago

Why choose Busbud?

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Busbud makes bus travel easy. We help travellers find a bus, plot routes, and book intercity bus tickets all over the world. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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