Bus Tickets from Durham, NC, US to Chicago

Next departures

Next departures for Durham to Chicago on October 6
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus
Durham Greyhound Bus Station
Chicago 95Th & Dan RyanCheapestFastest

Last refresh of the prices: Yesterday at 11:01 PM EDT.

Accepted payments

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Compare 2 ways to go from Durham to Chicago.

Bus
Average Price$81 - $271Average Duration1d 2h
25kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average Price$198 - $367Average Duration1d 15h
91kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Durham to Chicago

Among the sustainable travel choices, the bus stands out as the good way to reach Chicago. The journey takes about 1 day, 2 hours 5 minutes and with fares starting at just $81, it presents an excellent value for a comfortable ride.

15bus per day
1d 2hAverage Duration
$81Cheapest ticket
25kgCO₂ emissions

Bus Durham, NC, US to Chicago: Trip Overview

Average ticket price$167
Average bus trip duration1d 2h
Number of daily buses15
Earliest bus departure1:10am
Distance612 miles (987 km)
Latest bus departure10:05pm

Durham to Chicago Bus

With Busbud, comparing and booking tickets for a bus from Durham to Chicago is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make it our job to connect you with the most dependable bus companies that cover bus service from Durham to Chicago.

From cheap bus tickets to more luxurious buses traveling from Durham to Chicago, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions for your trip Durham, NC, US - Chicago

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
10/04
$167
10/05
$170
Today
$172
10/07
No data
10/08
No data
10/09
No data
10/10
$109
10/11
$103
busbud logoThe cheapest trip from Durham, NC, US to Chicago was searched and found on Oct 11, 2025 with a price of $103

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Durham, NC, US to Chicago, as early as possible.

You can expect to pay from $103 to $291 for a bus ticket from Durham, NC, US to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at $103 which is on 2025-10-11.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while traveling from Durham to Chicago.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from Durham to Chicago.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Durham to Chicago that are otherwise impossible to come by with a plane.

Tune out to the fine sounds of your best music playlist on your bus trip from Durham to Chicago while indulging in miles on end of beautiful scenic views.

Did you know?

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

What's the cheapest way to go from Durham, NC, US to Chicago?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Durham, NC, US by bus?

Bus from Chicago to Durham, NC, US

You can also go to Chicago by train

Train from Durham, NC, US to Chicago

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud makes bus travel easy. We help travelers find a bus, plot routes, and book intercity bus tickets all over the world. With several language and currency options available, Busbud seeks to cater to international bus travelers no matter where they are in the world. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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