Bus Tickets from Durham, NC, US to Jacksonville, FL

Next departures

Next departures for Durham to Jacksonville on November 6
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus
Durham Greyhound Bus Station
Jacksonville Bus StationCheapest
FlixBus
Durham Greyhound Bus Station
Jacksonville Bus StationFastest
Greyhound Lines, Inc. + FlixBus
Durham Greyhound Bus Station
Jacksonville Bus StationNo tags
FlixBus
Durham Greyhound Bus Station
Jacksonville Bus StationNo tags
Greyhound Lines, Inc. + FlixBus
Durham Greyhound Bus Station
Jacksonville Bus StationNo tags

Last refresh of the prices: Yesterday at 2:05 PM EDT.

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Compare 2 ways to go from Durham to Jacksonville

busbud logoWe recommend taking the train

Among the sustainable travel choices, the train stands out as a good way to reach Jacksonville. The journey takes about 13 hours 31 minutes, and with fares starting at just US$60, it presents an excellent value for a comfortable ride.

2train per day
13h 31mAverage Duration
679 kmDistance
62kgCO₂ emissions
Bus
Average PriceUS$57 - US$226Average Duration16h 40m
17kg CO₂e
Train
Average PriceUS$60 - US$138Average Duration13h 31m
62kg CO₂e

Bus Durham, NC, US to Jacksonville, FL: Trip Overview

Average Ticket PriceUS$111
Average Bus Trip Duration16h 40m
Number of daily buses4
Earliest bus departure1:10am
Distance681 km
Latest bus departure10:05pm

Durham to Jacksonville Bus

Busbud helps you find a bus from Durham to Jacksonville. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make it our job to connect you with the most dependable bus companies that cover bus service from Durham to Jacksonville.

Whether it is cheap bus tickets or more luxurious buses going to Jacksonville from Durham, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Durham, NC, US - Jacksonville, FL

  1. How far is Durham from Jacksonville?

    The distance covered from Durham to Jacksonville is 681 km (422 miles).

  2. What are the departure and arrival locations for buses traveling from Durham to Jacksonville?

    Buses traveling this route start their trip at Durham Greyhound Bus Station, in Durham, and end it at Jacksonville Amtrak Station, in Jacksonville.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
10-29
US$69
10-30
US$114
Today
US$115
11-01
No data
11-02
No data
11-03
No data
11-04
No data
11-05
No data
busbud logoThe cheapest trip from Durham, NC, US to Jacksonville, FL was searched and found on Oct 29, 2025 with a price of US$69

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Durham, NC, US to Jacksonville, FL, as early as possible.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Durham and Jacksonville!

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Durham to Jacksonville.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Durham to Jacksonville.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Durham to Jacksonville.

Did you know?

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

Will you be returning to Durham, NC, US by bus?

Bus from Jacksonville, FL to Durham, NC, US

You can also go to Jacksonville, FL by train

Train from Durham, NC, US to Jacksonville, FL

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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