Bus Tickets from Durham, NC, US to Jacksonville, FL

Next departures

Next departures for Durham to Jacksonville on November 2
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus
    		Durham Greyhound Bus Station
    		Jacksonville Bus StationCheapestFastest
    FlixBus
      		Durham Greyhound Bus Station
      		Jacksonville Bus StationNo tags
      FlixBus
        		Durham Greyhound Bus Station
        		Jacksonville Bus StationNo tags
        FlixBus
          		Durham Greyhound Bus Station
          		Jacksonville Bus StationNo tags

          Last refresh of the prices: Today at 5:34 AM EDT.

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          Compare 2 ways to go from Durham to Jacksonville

          We recommend taking the train

          Among the sustainable travel choices, the train stands out as the good way to reach Jacksonville. The journey takes about 13 hours 31 minutes and with fares starting at just $60, it presents an excellent value for a comfortable ride.

          2train per day
          13h 31mAverage Duration
          421 milesDistance
          62kgCO₂ emissions
          Bus
          		Average Price$57 - $226Average Duration16h 40m
          17kg CO₂e
          Train
          		Average Price$60 - $138Average Duration13h 31m
          62kg CO₂e

          Bus Durham, NC, US to Jacksonville, FL: Trip Overview

          Average ticket price$111
          Average bus trip duration16h 40m
          Number of daily buses4
          Earliest bus departure1:10am
          Distance423 miles (681 km)
          Latest bus departure10:05pm

          Durham to Jacksonville Bus

          Busbud helps you find a bus from Durham to Jacksonville. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

          We make it our job to connect you with the most dependable bus companies that cover bus service from Durham to Jacksonville.

          Whether it is cheap bus tickets or more luxurious buses going to Jacksonville from Durham, we help you find what you're looking for based on how much of a budget you have.

          Frequently asked questions for your trip Durham, NC, US - Jacksonville, FL

          Find cheapest prices for buses

          Price is for a one-way ticket for one passenger and based on past searches.

          Best price found
          10/30
          $114
          10/31
          $115
          Today
          No data
          11/02
          $137
          11/03
          No data
          11/04
          No data
          11/05
          No data
          11/06
          $66
          busbud logoThe cheapest trip from Durham, NC, US to Jacksonville, FL was searched and found on Nov 6, 2025 with a price of $66

          To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Durham, NC, US to Jacksonville, FL, as early as possible.

          You can expect to pay from $66 to $176 for a bus ticket from Durham, NC, US to Jacksonville, FL based on the last 2 days. You can expect to find the cheapest price for the trip at $66 which is on 2025-11-06.

          About Bus Travel

          Bus Travel Tips

          Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Durham and Jacksonville!

          From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from Durham to Jacksonville.

          Buses are energy-efficient. Carrying a passenger over 100 kms by bus only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Durham to Jacksonville.

          Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Durham to Jacksonville.

          Did you know?

          Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

          One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

          9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

          Will you be returning to Durham, NC, US by bus?

          Bus from Jacksonville, FL to Durham, NC, US

          You can also go to Jacksonville, FL by train

          Train from Durham, NC, US to Jacksonville, FL

          Why choose Busbud?

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