Next departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Durham Greyhound Bus Station | Jacksonville Bus Station | Cheapest | |||||
| Durham Greyhound Bus Station | Jacksonville Bus Station | Fastest | |||||
Greyhound Lines, Inc. + FlixBus | Durham Greyhound Bus Station | Jacksonville Bus Station | No tags | |||||
| Durham Greyhound Bus Station | Jacksonville Bus Station | No tags | |||||
Greyhound Lines, Inc. + FlixBus | Durham Greyhound Bus Station | Jacksonville Bus Station | No tags |
Last refresh of the prices: Yesterday at 2:05 PM EDT.
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Compare 2 ways to go from Durham to Jacksonville
Among the sustainable travel choices, the train stands out as the good way to reach Jacksonville. The journey takes about 13 hours 31 minutes and with fares starting at just $60, it presents an excellent value for a comfortable ride.
Bus Durham, NC, US to Jacksonville, FL: Trip Overview
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Durham to Jacksonville Bus
Busbud helps you find a bus from Durham to Jacksonville. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.
We make it our job to connect you with the most dependable bus companies that cover bus service from Durham to Jacksonville.
Whether it is cheap bus tickets or more luxurious buses going to Jacksonville from Durham, we help you find what you're looking for based on how much of a budget you have.
Where are the popular stops in Durham and Jacksonville?
Frequently asked questions for your trip Durham, NC, US - Jacksonville, FL
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Durham, NC, US to Jacksonville, FL was searched and found on Oct 29, 2025 with a price of $69To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Durham, NC, US to Jacksonville, FL, as early as possible.
About Bus Travel
Bus Travel Tips
Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Durham and Jacksonville!
From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from Durham to Jacksonville.
Buses are energy-efficient. Carrying a passenger over 100 kms by bus only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Durham to Jacksonville.
Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Durham to Jacksonville.
Did you know?
Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!
One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.
9.2% of ground transportation in Europe is done by bus versus 7.4% by train.
Top traveled bus routes
Why choose Busbud?
The Best Way To Book Bus and Train Tickets
Busbud helps you easily search, compare and book intercity bus tickets on a worldwide scale with our comprehensive list of bus routes and schedules. With several language and currency options available, Busbud seeks to cater to international bus travelers no matter where they are in the world. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.
People from around the world trust Busbud
Popular Buses Connecting Durham
Buses Leaving from Durham
- Bus from Durham to Greensboro
- Bus Durham - Atlanta
- Durham - York
- Bus from Durham to Asheville
- Bus Durham - Winston-Salem
- Durham - Toronto
- Bus from Durham to Washington
- Bus Durham - New York City
- Durham - Charlotte
- Bus from Durham to Miami
- Bus Durham - Wilmington
- Durham - Richmond
- Bus from Durham to Burlington
- Bus Durham - Baltimore
- Durham - Henderson
Buses Going to Durham
- Bus from Charlotte to Durham
- Bus Asheville - Durham
- Atlanta - Durham
- Bus from Corning to Durham
- Bus McKinney - Durham
- Toronto - Durham
- Bus from New York City to Durham
- Bus Washington - Durham
- Fayetteville - Durham
- Bus from Richmond to Durham
- Bus Baltimore - Durham
- Burlington - Durham
- Bus from Winston-Salem to Durham
- Bus Raleigh - Durham
- Charlottesville - Durham
Popular Buses Connecting Jacksonville
Buses Leaving from Jacksonville
- Bus from Jacksonville to Jacksonville
- Bus Jacksonville - Miami
- Jacksonville - Atlanta
- Bus from Jacksonville to Savannah
- Bus Jacksonville - Gainesville
- Jacksonville - Gainesville
- Bus from Jacksonville to Orlando
- Bus Jacksonville - Tallahassee
- Jacksonville - Tampa
- Bus from Jacksonville to New York City
- Bus Jacksonville - Fort Lauderdale
- Jacksonville - West Palm Beach
- Bus from Jacksonville to Ocala
- Bus Jacksonville - Houston
- Jacksonville - Dallas
Buses Going to Jacksonville
- Bus from Jacksonville to Jacksonville
- Bus Orlando - Jacksonville
- Tampa - Jacksonville
- Bus from Miami to Jacksonville
- Bus San Marcos - Jacksonville
- Charlotte - Jacksonville
- Bus from Atlanta to Jacksonville
- Bus Gainesville - Jacksonville
- Tallahassee - Jacksonville
- Bus from Fort Lauderdale to Jacksonville
- Bus New York City - Jacksonville
- Lake City - Jacksonville
- Bus from Ocala to Jacksonville
- Bus Charleston - Jacksonville
- Fort Myers - Jacksonville
Popular routes in this country
- Bus from Fort Lauderdale to Orlando
- Bus Dallas - Houston
- Albany - New York City
- Bus from Las Vegas to Los Angeles
- Bus Tampa - Miami
- Austin - Dallas
- Bus from Dallas to Austin
- Bus Seattle - Leavenworth
- Miami - Tampa
- Bus from Austin to Houston
- Bus Houston - San Antonio
- Houston - Austin
- Bus from San Antonio to Houston
- Bus Atlanta - Orlando
- Dallas - San Antonio