Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Price and booking link |
|---|---|---|---|---|---|---|---|
Greyhound + FlixBus | Bus | Florence, SC | Birmingham Greyhound Bus Station | ||||
FlixBus + Greyhound | Bus | Florence, SC | Birmingham Greyhound Bus Station | ||||
FlixBus + Greyhound | Bus | Bus station | Birmingham Greyhound Bus Station | ||||
Greyhound + FlixBus | Bus | Bus station | Birmingham Greyhound Bus Station | ||||
FlixBus + Greyhound | Bus | Bus station | Birmingham Greyhound Bus Station |
Compare 2 ways to go from Florence to Birmingham
Among the sustainable travel choices, the Bus stands out as a good way to reach Birmingham. The journey takes about 16 hours 45 minutes, and with fares starting at just CLP 66,162, it presents an excellent value for a comfortable ride.
Bus stations and stops in Florence and Birmingham
Stops in Florence
- A
Florence Bus Station
619 S Irby St, Florence, SC 29501, USA - B
TA Travel Center - Florence
2301 W Lucas St, Florence, SC 29501, USA
Stops in Birmingham
- A
Birmingham Greyhound Bus Station
1801 Morris Ave, 35203 Birmingham, AL - B
McDonald's - Birmingham
2427 Acton Rd, Vestavia Hills, AL 35243, USA
Compare bus companies
Based on 88123 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi‑Fi. Greyhound ticket prices on this trip start at CLP 66,162
Frequently asked questions about travelling from Florence, SC, US to Birmingham, US by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Florence to Birmingham?
The cheapest bus tickets from Florence to Birmingham start from CLP 66,162. The average price for this route is around CLP 75,273. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Florence to Birmingham?
The average bus travel time from Florence to Birmingham is 16h 45m, covering a distance of 655 km. The quickest bus can get you there in 10h 50m and is operated by Greyhound.
Which bus companies service the Florence to Birmingham route?
Several major bus companies operate on this route with 3 buses available per day.
What are the earliest and latest departure times for the bus from Florence to Birmingham?
The earliest bus departs from Florence to Birmingham at 12:05am. And the latest bus departs at 7:20pm.
What are the CO₂ emissions for the bus trip from Florence to Birmingham?
A bus trip from Florence to Birmingham generates an estimated 16.360400000000002 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Florence, SC, US to Birmingham, US was searched and found on Sep 8, 2026 with a price of CLP 62,659To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Florence, SC, US to Birmingham, US, as early as possible.
You can expect to pay from CLP 62,659 to CLP 67,933 for a bus ticket from Florence, SC, US to Birmingham, US based on the last 2 days. You can expect to find the cheapest price for the trip at CLP 62,659 which is on 2026-09-08.
What's the cheapest way to go from Florence, SC, US to Birmingham, US?
The Bus is the cheapest travel choice for this destination
