Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Price and booking link |
|---|---|---|---|---|---|---|---|
Greyhound + FlixBus | Bus | Florence, SC | Birmingham Greyhound Bus Station | ||||
FlixBus + Greyhound | Bus | Florence, SC | Birmingham Greyhound Bus Station | ||||
FlixBus + Greyhound | Bus | Florence, SC | Birmingham Greyhound Bus Station | ||||
FlixBus + Greyhound | Bus | Bus station | Birmingham Greyhound Bus Station | ||||
FlixBus + Greyhound | Bus | Bus station | Birmingham Greyhound Bus Station |
Compare 2 ways to go from Florence to Birmingham
Among the sustainable travel choices, the Bus stands out as a good way to reach Birmingham. The journey takes about 13 hours 45 minutes and with fares starting at just ¥12,506, it presents an excellent value for a comfortable ride.
Bus stations and stops in Florence and Birmingham
Stops in Florence
- A
Florence Bus Station
619 S Irby St, Florence, SC 29501, USA - B
TA Travel Center - Florence
2301 W Lucas St, Florence, SC 29501, USA
Stops in Birmingham
- A
Birmingham Greyhound Bus Station
1801 Morris Ave, 35203 Birmingham, AL - B
McDonald's - Birmingham
2427 Acton Rd, Vestavia Hills, AL 35243, USA
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Florence, SC, US to Birmingham, US by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Florence to Birmingham?
The cheapest bus tickets from Florence to Birmingham start from ¥12,506. The average price for this route is around ¥15,169. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Florence to Birmingham?
The average bus trip duration from Florence to Birmingham is 13h 45m, covering a distance of 406 miles (655 km). The quickest bus can get you there in 10h 50m and is operated by Greyhound.
Which bus companies service the Florence to Birmingham route?
Several major bus companies operate on this route with 3 buses available per day.
What is the earliest and latest departure time for the bus from Florence to Birmingham?
The earliest bus departs from Florence to Birmingham at 5:45am. And the latest bus departs at 7:00pm.
What are the CO₂ emissions for the bus trip from Florence to Birmingham?
A bus trip from Florence to Birmingham generates an estimated 16.360475 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Florence, SC, US to Birmingham, US was searched and found on Jul 23, 2026 with a price of ¥12,146To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Florence, SC, US to Birmingham, US, as early as possible.
You can expect to pay from ¥12,146 to ¥12,727 for a bus ticket from Florence, SC, US to Birmingham, US based on the last 2 days. You can expect to find the cheapest price for the trip at ¥12,146 which is on 2026-07-23.
What's the cheapest way to go from Florence, SC, US to Birmingham, US?
The Bus is the cheapest travel choice for this destination
