Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Price and booking link |
|---|---|---|---|---|---|---|---|
 | Bus
| Framingham Intermodal - 2 Franklin St | Downtown Greyhound Station | ||||
| Bus
| Framingham Intermodal - 2 Franklin St | Chicago 95Th & Dan Ryan | ||||
Greyhound + FlixBus | Bus
| Framingham Intermodal - 2 Franklin St | 537-517 W. Jackson Blvd | ||||
FlixBus + Greyhound | Bus
| Framingham Intermodal - 2 Franklin St | 537-517 W. Jackson Blvd | ||||
Greyhound + FlixBus | Bus
| Framingham Intermodal - 2 Franklin St | 537-517 W. Jackson Blvd |
Compare 2 ways to go from Framingham to Chicago
Among the sustainable travel choices, the Train stands out as a good way to reach Chicago. The journey takes about 21 hours 47 minutes, and with fares starting at just $226, it presents an excellent value for a comfortable ride.
Bus stations and stops in Framingham and Chicago
Stops in Framingham
- A
Framingham Flutie Pass Bus Stop
43 Flutie Pass Commuter Lot (Park and Ride Lot - Routes 9 & 30 - Exit 13 off I-90), Framingham, MA 01701 - B
Shoppers World Bus Stop
1 Worcester Rd, Framingham, MA 01701, USA - C
Route 9 East Park and Ride
1672 Worcester Rd, Framingham, MA 01702, USA
Stops in Chicago
- A
Downtown Greyhound Station
630 W Harrison St, Chicago, IL 60607, USA - C
Polk St & Canal St
500-536 W Polk St, Chicago IL 60607, USA - D
Tornado Bus S Kedzie Ave
2807 S Kedzie Ave, Chicago, IL 60623, USA - E
Cumberland CTA
5800 N Cumberland Ave, Chicago, IL 60631, USA - F
Turimex California Ave
2139 S California Ave, Chicago, IL 60608, USA
Compare bus companies
Based on 88240 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi‑Fi. Greyhound ticket prices on this trip start at $176
Frequently asked questions about travelling from Framingham to Chicago by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Framingham to Chicago?
The cheapest bus tickets from Framingham to Chicago start from $176. The average price for this route is around $234. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Framingham to Chicago?
The average bus travel time from Framingham to Chicago is 1d 7h, covering a distance of 1339 km. The quickest bus can get you there in 1d 6h and is operated by Greyhound.
Which bus companies service the Framingham to Chicago route?
Several major bus companies operate on this route with 5 buses available per day.
What are the earliest and latest departure times for the bus from Framingham to Chicago?
The earliest bus departs from Framingham to Chicago at 11:35am. And the latest bus departs at 2:45pm.
What are the CO₂ emissions for the bus trip from Framingham to Chicago?
A bus trip from Framingham to Chicago generates an estimated 33.45315 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Framingham to Chicago was searched and found on Oct 15, 2026 with a price of $230To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Framingham to Chicago, as early as possible.
What's the cheapest way to go from Framingham to Chicago?
The Bus is the cheapest travel choice for this destination
