Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Gainesville Bus Stop | Panama City Beach Station | No tags | ||||
| Bus | Gainesville Bus Stop | Panama City Beach Station | No tags | ||||
| Bus | Gainesville Bus Stop | Panama City Beach Station | No tags | ||||
| Bus | Gainesville Bus Stop | Panama City Beach Station | No tags | ||||
| Bus | Gainesville Bus Stop | Panama City Beach Station | No tags |
Get from Gainesville to Panama City
The journey takes about 6 hours 40 minutes, and with fares starting at just $78, it presents an excellent value for a comfortable ride.
Where are the popular stops in Gainesville and Panama City?
Stops in Gainesville
- A700 SE 3rd St, Gainesville, FL 32601
- B3509 SW Williston Rd, Gainesville, FL 32608, USA
- C101 NE 23rd Ave, Gainesville, FL 32609
Compare bus companies
Based on 87500 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. Greyhound ticket prices on this trip start at $78
Frequently asked questions about travelling from Gainesville, FL to Panama City, US by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Gainesville to Panama City?
The cheapest bus tickets from Gainesville to Panama City start from $78. The average price for this route is around $129. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Gainesville to Panama City?
The average bus travel time from Gainesville to Panama City is 6h 40m, covering a distance of 338 km. The quickest bus can get you there in 6h 40m and is operated by Greyhound.
Which bus companies service the Gainesville to Panama City route?
Several major bus companies operate on this route with 1 buses available per day.
What are the earliest and latest departure times for the bus from Gainesville to Panama City?
The earliest bus departs from Gainesville to Panama City at 8:20am. And the latest bus departs at 4:00pm.
What are the CO₂ emissions for the bus trip from Gainesville to Panama City?
A bus trip from Gainesville to Panama City generates an estimated 8 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Gainesville, FL to Panama City, US was searched and found on Jan 16, 2026 with a price of $89To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Gainesville, FL to Panama City, US, as early as possible.
You can expect to pay from $89 to $109 for a bus ticket from Gainesville, FL to Panama City, US based on the last 2 days. You can expect to find the cheapest price for the trip at $89 which is on 2026-01-16.
