Bus Tickets from Gainesville, GA to San Diego, CA

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TodayMay 18
from US$269
TomorrowMay 19
TueMay 20
WedMay 21
ThuMay 22
FriMay 23
SatMay 24
SunMay 25

Cheap buses leaving today

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: May 18 at
    Departure city: Gainesville
    Departure location: Gainesville (Mart 24/7)
    Arrival time: May 23 at
    Destination city: San Diego
    Destination location: 5716 Hardy Ave
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: May 18 at
    Departure city: Gainesville
    Departure location: Gainesville (Mart 24/7)
    Arrival time: May 21 at
    Destination city: San Diego
    Destination location: UCSD Health La Jolla Station
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • Departure time: May 18 at
    Departure city: Gainesville
    Departure location: Gainesville (Mart 24/7)
    Arrival time: May 21 at
    Destination city: San Diego
    Destination location: San Diego (Old Town-FlixBus)
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • Departure time: May 18 at
    Departure city: Gainesville
    Departure location: Gainesville (Mart 24/7)
    Arrival time: May 21 at
    Destination city: San Diego
    Destination location: Greyhound Bus Stop
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: May 18 at
    Departure city: Gainesville
    Departure location: Gainesville (Mart 24/7)
    Arrival time: May 21 at
    Destination city: San Diego
    Destination location: UCSD Health La Jolla Station
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:

Last refresh of the prices: Yesterday at 8:49 AM EDT.

Prices and availability are subject to change.

Accepted payments

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Bus Gainesville to San Diego: Trip Overview

Average Ticket PriceUS$287
Average Bus Trip Duration2d 14h
Number of daily buses5
Earliest bus departure10:15am
Distance3087 km
Latest bus departure10:30pm

Gainesville to San Diego Bus

Busbud helps you find a bus from Gainesville to San Diego. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make sure you can find a bus service from Gainesville to San Diego from the most reliable bus companies operating this trip.

Whether it is cheap bus tickets or more luxurious buses going to San Diego from Gainesville, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Gainesville - San Diego

  1. How long is the bus ride from Gainesville to San Diego?

    The typical travel time from Gainesville to San Diego by bus is around 2d 14h. For the shortest travel time, select the fastest bus available, which will take you to San Diego in about 2d 10h.

  2. How far is Gainesville from San Diego?

    Gainesville and San Diego are 3086 km (1913 miles) apart.

  3. What are the departure and arrival locations for buses traveling from Gainesville to San Diego?

    Buses departing from La Flor de Jalisco Bus Stop in Gainesville will take you to Mission Valley Sheraton in San Diego.

  4. What is the cheapest way to get from Gainesville to San Diego?

    The least expensive way to go from Gainesville to San Diego would be going by bus. Starting at US$282, this bus is the most cost-effective option for your journey.

  5. How much does it cost to take the bus from Gainesville to San Diego?

    The bus from Gainesville to San Diego will cost you US$287, on average.

  6. Can I take an overnight bus from Gainesville to San Diego?

    Yes! If you're heading from Gainesville to San Diego, you'll find buses departing until 10:30pm and arriving the next day.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
05-16
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05-17
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Today
US$297
05-19
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05-20
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05-21
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05-22
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05-23
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busbud logoThe cheapest trip from Gainesville to San Diego was searched and found on May 18, 2025 with a price of US$297

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Gainesville to San Diego, as early as possible.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Gainesville and San Diego!

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Gainesville to San Diego, get comfy and count the stars.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Gainesville to San Diego.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Gainesville to San Diego.

Did you know?

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

Will you be returning to Gainesville by bus?

Bus from Gainesville to San Diego

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