Bus Tickets from Gainesville, FL to St. Louis

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Previously seen trips

One passenger / one way

  • Departure time: September 30 at
    Departure city: Gainesville
    Departure location: Gainesville Bus Stop
    Arrival time: October 1 at
    Destination city: St. Louis
    Destination location: Gateway Station
    Operated by: Greyhound + FlixBus
    Greyhound + FlixBus
    Vehicle: BusDuration:
  • Departure time: September 30 at
    Departure city: Gainesville
    Departure location: Gainesville Bus Stop
    Arrival time: October 1 at
    Destination city: St. Louis
    Destination location: Gateway Station
    Operated by: FlixBus + Greyhound
    FlixBus + Greyhound
    Vehicle: BusDuration:
  • Departure time: September 30 at
    Departure city: Gainesville
    Departure location: Gainesville Bus Stop
    Arrival time: October 1 at
    Destination city: St. Louis
    Destination location: Gateway Station
    Operated by: GreyhoundGreyhound
    Vehicle: BusDuration:
  • Departure time: September 30 at
    Departure city: Gainesville
    Departure location: Gainesville Bus Stop
    Arrival time: October 1 at
    Destination city: St. Louis
    Destination location: Gateway Station
    Operated by: GreyhoundGreyhound
    Vehicle: BusDuration:
  • Departure time: September 30 at
    Departure city: Gainesville
    Departure location: Rosa Parks Station
    Arrival time: October 1 at
    Destination city: St. Louis
    Destination location: Gateway Station
    Operated by: FlixBus + Greyhound
    FlixBus + Greyhound
    Vehicle: BusDuration:

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Bus Gainesville, FL to St. Louis: Trip Overview

Average Ticket PriceUS$128
Average Bus Trip Duration23h 45m
Number of daily buses6
Earliest bus departure1:10am
Distance1225 km
Latest bus departure10:40pm

Gainesville to St. Louis Bus

Busbud helps you find a bus from Gainesville to St. Louis. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make sure you can find a bus service from Gainesville to St. Louis from the most reliable bus companies operating this trip.

Discover how much the bus trip from Gainesville to St. Louis will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Gainesville, FL - St. Louis

  1. What is the travel distance from Gainesville to St. Louis?

    The distance between Gainesville and St. Louis is around 1234 km (765 miles).

  2. What are the departure and arrival locations for buses traveling from Gainesville to St. Louis?

    Buses traveling this route start their trip at Rosa Parks Station, in Gainesville, and end it at Gateway Station, in St. Louis.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
08-31
US$107
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busbud logoThe cheapest trip from Gainesville, FL to St. Louis was searched and found on Aug 31, 2025 with a price of US$107

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Gainesville, FL to St. Louis, as early as possible.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Gainesville and St. Louis!

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Gainesville to St. Louis, get comfy and count the stars.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Gainesville to St. Louis will emit less CO2 than a car or an airplane.

Tune out to the fine sounds of your best music playlist on your bus trip from Gainesville to St. Louis while indulging in miles on end of beautiful scenic views.

Did you know?

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

Will you be returning to Gainesville, FL by bus?

Bus from St. Louis to Gainesville, FL

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