Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound Lines, Inc. | Bus | 1116 Woodruff Rd | Cleveland Bus Station | Cheapest | ||||
 | Bus | 1116 Woodruff Rd | Cleveland Bus Station | Fastest |
Last refresh of the prices: Yesterday at 4:24 PM EST.
Compare 2 ways to go from Greenville to Cleveland
Among the sustainable travel choices, the Bus stands out as a good way to reach Cleveland. The journey takes about 1 day, 5 hours 45 minutes, and with fares starting at just $227, it presents an excellent value for a comfortable ride.
Where are the popular stops in Greenville and Cleveland?
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Frequently asked questions about travelling from Greenville, SC to Cleveland, OH, US by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Greenville to Cleveland?
The cheapest bus tickets from Greenville to Cleveland start from $227. The average price for this route is around $305. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Greenville to Cleveland?
The average bus travel time from Greenville to Cleveland is 1d 5h, covering a distance of 745 km. The quickest bus can get you there in 19h 50m and is operated by Greyhound.
Which bus companies service the Greenville to Cleveland route?
What are the earliest and latest departure times for the bus from Greenville to Cleveland?
The earliest bus departs from Greenville to Cleveland at 2:45pm. And the latest bus departs at 10:00pm.
What are the CO₂ emissions for the bus trip from Greenville to Cleveland?
A bus trip from Greenville to Cleveland generates an estimated 19 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Greenville to Cleveland?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87500 reviews.
Which bus company has the best Wi-Fi from Greenville to Cleveland?
Based on Busbud reviews, the bus company FlixBus has the highest Wi-Fi rating with a score of 2.7.
Which bus company has the best on-time performance from Greenville to Cleveland?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Greenville to Cleveland?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Greenville, SC to Cleveland, OH, US was searched and found on Jan 17, 2026 with a price of $134To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Greenville, SC to Cleveland, OH, US, as early as possible.
You can expect to pay from $134 to $245 for a bus ticket from Greenville, SC to Cleveland, OH, US based on the last 2 days. You can expect to find the cheapest price for the trip at $134 which is on 2026-01-17.
What's the cheapest way to go from Greenville, SC to Cleveland, OH, US?
The Bus is the cheapest travel choice for this destination
