Bus Tickets from Harrisburg, PA to Roanoke, VA

Find affordable bus tickets from Harrisburg, PA to Roanoke, VA with flexible options. Book your trip now

Join 75M+ travelers booking 2M+ routes across 85+ countries.
Enjoy our 24/7 customer service to assist you at every step.
Cancel anytime and receive a 100% refund, no reason needed.
TodayMay 14
from US$122
TomorrowMay 15
from US$89
FriMay 16
from US$106
SatMay 17
from US$78
SunMay 18
from US$93
MonMay 19
TueMay 20
from US$96
WedMay 21

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest + Fastest
    Departure time: May 15 at
    Departure city: Harrisburg
    Departure location: Harrisburg Bus Station
    Arrival time: May 16 at
    Destination city: Roanoke
    Destination location: Roanoke Bus Stop
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:

Last refresh of the prices: Last Thursday at 8:00 PM EDT.

Prices and availability are subject to change.

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Compare 2 ways to go from Harrisburg to Roanoke

Average PriceUS$65 - US$159Average Duration21h
11kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Average PriceUS$235 - US$235Average Duration10h 46m
39kg CO₂e1 out of 5 stars
Fastest
busbud logoBusbud recommends taking the bus from Harrisburg to Roanoke

Among the sustainable travel choices, the bus stands out as a good way to reach Roanoke. The journey takes about 21 hours, and with fares starting at just US$65, it presents an excellent value for a comfortable ride.

1bus per day
21hAverage Duration
US$65Cheapest ticket
11kgCO₂ emissions

Bus Harrisburg to Roanoke: Trip Overview

Average Ticket PriceUS$92
Average Bus Trip Duration21h
Number of daily buses1
Earliest bus departure2:30pm
Distance426 km
Latest bus departure3:05pm

Harrisburg to Roanoke Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Harrisburg to Roanoke.

Bus service from Harrisburg to Roanoke will be provided by the most trusted bus companies.

Discover how much the bus trip from Harrisburg to Roanoke will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Harrisburg - Roanoke

  1. How long is the bus trip from Harrisburg to Roanoke?

    The typical travel time from Harrisburg to Roanoke by bus is around 21h. If you're looking for the fastest way to get there, you'll find a bus doing the trip in about 21h.

  2. How far is Harrisburg from Roanoke?

    The distance between Harrisburg and Roanoke is around 427 km (265 miles).

  3. What are the departure and arrival locations for buses traveling from Harrisburg to Roanoke?

    Buses traveling this route start their trip at Harrisburg Bieber Greyhound Station, in Harrisburg, and end it at Salem - Exit 140 Park & Ride, in Roanoke.

  4. What is the cheapest way to go from Harrisburg to Roanoke?

    The least expensive option to go from Harrisburg to Roanoke would be going by bus. The ticket price for this bus starts at US$65, making this your best choice for this trip.

  5. How much does it cost to take the bus from Harrisburg to Roanoke?

    Taking the bus from Harrisburg to Roanoke costs on average US$92.

  6. Can I take an overnight bus from Harrisburg to Roanoke?

    Yes! Catch buses leaving from Harrisburg until 3:05pm and reaching Roanoke on the following day.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
05-12
US$109
05-13
US$95
Today
US$114
05-15
US$82
05-16
US$98
05-17
US$70
05-18
US$85
05-19
US$79
busbud logoThe cheapest trip from Harrisburg to Roanoke was searched and found on May 17, 2025 with a price of US$70

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Harrisburg to Roanoke, as early as possible.

You can expect to pay from US$70 to US$114 for a bus ticket from Harrisburg to Roanoke based on the last 2 days. You can expect to find the cheapest price for the trip at US$70 which is on 2025-05-17.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Harrisburg to Roanoke but it'll also be endearing to native speakers who will surely appreciate your effort.

Much more than a mere vehicle taking you from Harrisburg to Roanoke, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Harrisburg to Roanoke will emit less CO2 than a car or an airplane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Harrisburg to Roanoke.

Did you know?

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

What's the cheapest way to go from Harrisburg to Roanoke?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Harrisburg by bus?

Bus from Harrisburg to Roanoke

You can also go to Roanoke by train

Train from Harrisburg to Roanoke

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. Use Busbud to book your trip online, in your own language and currency, wherever you are. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

People from around the world trust Busbud

Popular Buses Connecting Harrisburg

Buses Leaving from Harrisburg

Buses Going to Harrisburg

Popular Buses Connecting Roanoke

Buses Leaving from Roanoke

Buses Going to Roanoke