Bus Tickets from Harrisburg to San Diego, CA, US

Next departures

Next departures for Harrisburg to San Diego on September 23
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc. + FlixBus
Harrisburg Bus Station
San Diego (Old Town-FlixBus)Cheapest
Greyhound Lines, Inc. + FlixBus
Harrisburg Bus Station
UCSD Health La Jolla StationFastest
Greyhound Lines, Inc. + FlixBus
Harrisburg Bus Station
San Diego (Old Town-FlixBus)No tags
Greyhound Lines, Inc.
Harrisburg Bus Station
Greyhound Bus StopNo tags
Greyhound Lines, Inc. + FlixBus
Harrisburg Bus Station
UCSD Health La Jolla StationNo tags

Last refresh of the prices: Yesterday at 12:12 PM EDT.

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Compare 2 ways to go from Harrisburg to San Diego

Bus
Average PriceUS$235 - US$618Average Duration2d 23h
92kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average PriceUS$461 - US$506Average Duration3d 1h
334kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Harrisburg to San Diego

Among the sustainable travel choices, the bus stands out as a good way to reach San Diego. The journey takes about 2 days, 23 hours 35 minutes, and with fares starting at just US$235, it presents an excellent value for a comfortable ride.

13bus per day
2d 23hAverage Duration
US$235Cheapest ticket
92kgCO₂ emissions

Bus Harrisburg to San Diego, CA, US: Trip Overview

Average Ticket PriceUS$401
Average Bus Trip Duration2d 23h
Number of daily buses13
Earliest bus departure2:30am
Distance3662 km
Latest bus departure9:10pm

Harrisburg to San Diego Bus

With Busbud, comparing and booking tickets for a bus from Harrisburg to San Diego is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

Bus service from Harrisburg to San Diego will be provided by the most trusted bus companies.

Whether it is cheap bus tickets or more luxurious buses going to San Diego from Harrisburg, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Harrisburg - San Diego, CA, US

  1. What is the travel distance from Harrisburg to San Diego?

    The distance covered from Harrisburg to San Diego is 3668 km (2275 miles).

  2. What are the departure and arrival locations for buses traveling from Harrisburg to San Diego?

    Buses traveling this route start their trip at Harrisburg Bieber Greyhound Station, in Harrisburg, and end it at Mission Valley Sheraton, in San Diego.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
09-21
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09-22
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Today
US$258
09-24
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09-25
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09-26
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09-27
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09-28
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busbud logoThe cheapest trip from Harrisburg to San Diego, CA, US was searched and found on Sep 23, 2025 with a price of US$258

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Harrisburg to San Diego, CA, US, as early as possible.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Harrisburg to San Diego.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Much more than a mere vehicle taking you from Harrisburg to San Diego, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Harrisburg to San Diego.

Make a music playlist for your bus ride from Harrisburg to San Diego, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

What's the cheapest way to go from Harrisburg to San Diego, CA, US?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Harrisburg by bus?

Bus from San Diego, CA, US to Harrisburg

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. Use Busbud to book your trip online, in your own language and currency, wherever you are. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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