How much is the bus ticket from Houston to San Ysidro?

The cheapest bus tickets from Houston to San Ysidro start from $187. The average price for this route is around $424. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the bus ride from Houston to San Ysidro?

The average bus travel time from Houston to San Ysidro is 2d , covering a distance of 2077 km. The quickest bus can get you there in 1d 12h and is operated by Greyhound .

Which bus companies service the Houston to San Ysidro route?

Several major bus companies operate on this route with 17 buses available per day.

What are the earliest and latest departure times for the bus from Houston to San Ysidro?

The earliest bus departs from Houston to San Ysidro at 2:00am. And the latest bus departs at 11:20pm.

What are the CO₂ emissions for the bus trip from Houston to San Ysidro?

A bus trip from Houston to San Ysidro generates an estimated 52 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.

Bus Houston to San Ysidro from $189 | Refundable Tickets

Next bus departures

Next departures for Houston to San Ysidro on January 14
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound Lines, Inc.	Bus	11:10am	Downtown Gray & Smith	2d 1h	10:35am	San Ysidro Bus terminal	Cheapest
Greyhound Lines, Inc. + FlixBus	Bus	8:15am	Houston Bus Station	1d 16h	10:45pm	San Ysidro Bus terminal	Fastest
Greyhound Lines, Inc. + FlixBus	Bus	6:55pm	Houston Bus Station	1d 17h	10:35am	San Ysidro Bus terminal	No tags
FlixBus + Greyhound Lines, Inc.	Bus	11:25am	Houston Uptown/Upper Kirby	2d 1h	10:35am	San Ysidro Bus terminal	No tags
FlixBus + Greyhound Lines, Inc.	Bus	11:20pm	Baytown, 6800 Thompson Rd	2d 21h	6:20pm	San Ysidro Bus terminal	No tags

Next departures for Houston to San Ysidro on January 15
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Valley Transit + Greyhound Lines, Inc. + FlixBus	Bus	6:35am	Hillcroft Ave & Southwest Freeway	2d 12h	5:10pm	San Ysidro Greyhound Bus Station	Cheapest
	Bus	8:15am	Houston Bus Station	1d 12h	6:20pm	San Ysidro Bus terminal	Fastest
Greyhound Lines, Inc. + FlixBus	Bus	2:00am	Houston Bus Station	1d 14h	2:40pm	San Ysidro Bus terminal	No tags
FlixBus + Valley Transit + Greyhound Lines, Inc.	Bus	2:25pm	Downtown Gray & Smith	1d 22h	10:35am	San Ysidro Bus terminal	No tags
Greyhound Lines, Inc. + FlixBus	Bus	6:55pm	Houston Bus Station	1d 17h	10:35am	San Ysidro Bus terminal	No tags

Next departures for Houston to San Ysidro on January 16
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	8:15am	Houston Bus Station	1d 12h	6:20pm	San Ysidro Bus terminal	CheapestFastest
Greyhound Lines, Inc. + FlixBus	Bus	2:00am	Houston Bus Station	1d 14h	2:40pm	San Ysidro Bus terminal	No tags
Valley Transit + Greyhound Lines, Inc. + FlixBus	Bus	6:35am	Hillcroft Ave & Southwest Freeway	2d 6h	10:35am	San Ysidro Bus terminal	No tags
Greyhound Lines, Inc. + FlixBus	Bus	6:55pm	Houston Bus Station	1d 17h	10:35am	San Ysidro Bus terminal	No tags
FlixBus + Greyhound Lines, Inc.	Bus	6:00pm	Downtown Gray & Smith	1d 18h	10:35am	San Ysidro Bus terminal	No tags

Next departures for Houston to San Ysidro on January 17
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Valley Transit + Greyhound Lines, Inc. + FlixBus	Bus	6:35am	Hillcroft Ave & Southwest Freeway	2d 6h	10:35am	San Ysidro Bus terminal	Cheapest
	Bus	8:15am	Houston Bus Station	1d 12h	6:20pm	San Ysidro Bus terminal	Fastest
Greyhound Lines, Inc. + FlixBus	Bus	2:00am	Houston Bus Station	1d 14h	2:40pm	San Ysidro Bus terminal	No tags
Valley Transit + Greyhound Lines, Inc. + FlixBus	Bus	6:35am	Hillcroft Ave & Southwest Freeway	2d 12h	5:10pm	San Ysidro Greyhound Bus Station	No tags
Greyhound Lines, Inc. + FlixBus	Bus	6:55pm	Houston Bus Station	1d 17h	10:35am	San Ysidro Bus terminal	No tags

Next departures for Houston to San Ysidro on January 18
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Valley Transit + Greyhound Lines, Inc.	Bus	6:35am	Hillcroft Ave & Southwest Freeway	2d 7h	12:20pm	San Ysidro Bus terminal	Cheapest
	Bus	8:15am	Houston Bus Station	1d 12h	6:20pm	San Ysidro Bus terminal	Fastest
Greyhound Lines, Inc. + FlixBus	Bus	2:00am	Houston Bus Station	1d 14h	2:40pm	San Ysidro Bus terminal	No tags
	Bus	6:55pm	Houston Bus Station	1d 19h	12:20pm	San Ysidro Bus terminal	No tags
FlixBus + Greyhound Lines, Inc.	Bus	6:00pm	Downtown Gray & Smith	1d 20h	12:20pm	San Ysidro Bus terminal	No tags

Next departures for Houston to San Ysidro on January 19
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	8:15am	Houston Bus Station	1d 12h	6:20pm	San Ysidro Bus terminal	CheapestFastest
	Bus	6:55pm	Houston Bus Station	1d 19h	12:20pm	San Ysidro Bus terminal	No tags
FlixBus + Greyhound Lines, Inc.	Bus	6:00pm	Downtown Gray & Smith	1d 20h	12:20pm	San Ysidro Bus terminal	No tags
Valley Transit + Greyhound Lines, Inc.	Bus	6:35am	Hillcroft Ave & Southwest Freeway	2d 7h	12:20pm	San Ysidro Bus terminal	No tags
FlixBus + Greyhound Lines Mexico + Greyhound Lines, Inc.	Bus	7:35pm	Downtown Gray & Smith	2d 1h	6:45pm	San Ysidro Bus terminal	No tags

Last refresh of the prices: Last Saturday at 12:53 AM CST.

Get from Houston to San Ysidro

This route is served by bus only

The journey takes about 2 days, 15 minutes, and with fares starting at just $187, it presents an excellent value for a comfortable ride.

17bus per day

2d Average Duration

2077 kmDistance

52kgCO₂ emissions

Where are the popular stops in Houston and San Ysidro?

Stops in Houston

A
Hillcroft Ave & Southwest Freeway
6590 Southwest Fwy, Houston, TX 77074, USA
Visit page Map
B
Downtown Greyhound Station
2121 Main St, Houston, TX 77002
Map
C
Harrisburg Greyhound Station
7000 Harrisburg Blvd, Houston, TX 77011, USA
Map
D
Harrisburg Senda Station
7011 Harrisburg Blvd, Houston, TX 77011, USA
Visit page Map
E
Clay St & Louisiana St
600-698 Clay St, Houston, TX 77002, USA
Map
F
Lockwood Dr & Harvey Wilson Dr
820 Lockwood Dr, Houston, TX 77002, USA
Map

Stops in San Ysidro

A
San Ysidro Greyhound Bus Station
731 E San Ysidro Blvd, San Ysidro, CA 92173
Visit page Map

Compare bus companies

Greyhound

3.5/587,500 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Based on 87500 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. Greyhound ticket prices on this trip start at $187

US bus companies:FlixBus, BlaBlaCar Bus, Greyhound, ALSA, Intercape, Trenitalia, Big Sky

Frequently asked questions about travelling from Houston, US to San Ysidro, CA by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from Houston to San Ysidro?
The cheapest bus tickets from Houston to San Ysidro start from $187. The average price for this route is around $424. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Houston to San Ysidro?
The average bus travel time from Houston to San Ysidro is 2d , covering a distance of 2077 km. The quickest bus can get you there in 1d 12h and is operated by Greyhound.
Which bus companies service the Houston to San Ysidro route?
Several major bus companies operate on this route with 17 buses available per day.
What are the earliest and latest departure times for the bus from Houston to San Ysidro?
The earliest bus departs from Houston to San Ysidro at 2:00am. And the latest bus departs at 11:20pm.
What are the CO₂ emissions for the bus trip from Houston to San Ysidro?
A bus trip from Houston to San Ysidro generates an estimated 52 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

01-12

$376

01-13

$436

Today

No data

01-15

$389

01-16

$277

01-17

$398

01-18

$412

01-19

$277

The cheapest trip from Houston, US to San Ysidro, CA was searched and found on Jan 16, 2026 with a price of $277

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Houston, US to San Ysidro, CA, as early as possible.

You can expect to pay from $277 to $436 for a bus ticket from Houston, US to San Ysidro, CA based on the last 2 days. You can expect to find the cheapest price for the trip at $277 which is on 2026-01-16.