Next available departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Indianapolis Bus Station | Niagara Frontier Transportation Authority | Cheapest | |||||
FlixBus + Greyhound Lines, Inc. | Downtown Transit Center | Niagara Frontier Transportation Authority | Fastest | |||||
 | Greyhound Amtrak Station | Depew Station | No tags | |||||
FlixBus + Greyhound Lines, Inc. | Downtown Transit Center | Niagara Frontier Transportation Authority | No tags | |||||
| Greyhound Amtrak Station | Depew Station | No tags |
Last refresh of the prices: Yesterday at 5:50 PM EDT.
Compare 2 ways to go from Indianapolis to Buffalo
Among the sustainable travel choices, the Bus stands out as a good way to reach Buffalo. The journey takes about 17 hours 15 minutes, and with fares starting at just $127, it presents an excellent value for a comfortable ride.
Where are the popular stops in Indianapolis and Buffalo?
Stops in Buffalo
- B185 Ellicott St, Buffalo, NY 14203, USA
- C75 Exchange St, Buffalo, NY 14203, USA
Compare bus companies
Based on 87531 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi‑Fi. Greyhound ticket prices on this trip start at $132
Greyhound Indianapolis Buffalo recent customer reviews
The ticket I bought made me change buses 4 times and stoped more times, but it was not clear when I bought, all that discomforting situation was surprising for me.
Constanza P.
Frequently asked questions about travelling from Indianapolis to Buffalo, NY by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Indianapolis to Buffalo?
The cheapest bus tickets from Indianapolis to Buffalo start from $127. The average price for this route is around $191. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Indianapolis to Buffalo?
The average bus travel time from Indianapolis to Buffalo is 17h 15m, covering a distance of 701 km. The quickest bus can get you there in 19h 35m and is operated by Greyhound.
Which bus companies service the Indianapolis to Buffalo route?
Several major bus companies operate on this route with 3 buses available per day, including services from Greyhound, Amtrak.
What are the earliest and latest departure times for the bus from Indianapolis to Buffalo?
The earliest bus departs from Indianapolis to Buffalo at 12:15am. And the latest bus departs at 11:30pm.
What are the CO₂ emissions for the bus trip from Indianapolis to Buffalo?
A bus trip from Indianapolis to Buffalo generates an estimated 17.50835 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Indianapolis to Buffalo?
According to Busbud customers, the highest-rated bus company on this route is Amtrak, with an average rating of 4.1 out of 5 stars based on 5780 reviews.
Which bus company has the best Wi-Fi from Indianapolis to Buffalo?
Based on Busbud reviews, the bus company Amtrak has the highest Wi-Fi rating with a score of 3.6.
Which bus company has the best on-time performance from Indianapolis to Buffalo?
According to Busbud traveller reviews, the most punctual bus company on this route is Amtrak, with a punctuality rating of 3.8 out of 5 stars.
Which bus company has the cleanest buses from Indianapolis to Buffalo?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Amtrak, with a cleanliness rating of 4.5 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Indianapolis to Buffalo, NY was searched and found on Mar 30, 2026 with a price of $154To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Indianapolis to Buffalo, NY, as early as possible.
You can expect to pay from $154 to $2,130 for a bus ticket from Indianapolis to Buffalo, NY based on the last 2 days. You can expect to find the cheapest price for the trip at $175 which is on 2026-04-06.
What's the cheapest way to go from Indianapolis to Buffalo, NY?
The Bus is the cheapest travel choice for this destination
