Bus Tickets from Indianapolis, IN to Buffalo, NY

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Compare 2 ways to go from Indianapolis to Buffalo

Bus
Average PriceUS$79 - US$217Average Duration17h 45m
17kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average PriceUS$161 - US$218Average Duration1d 2h
65kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Indianapolis to Buffalo

Among the sustainable travel choices, the bus stands out as a good way to reach Buffalo. The journey takes about 17 hours 45 minutes, and with fares starting at just US$79, it presents an excellent value for a comfortable ride.

5bus per day
17h 45mAverage Duration
US$79Cheapest ticket
17kgCO₂ emissions

Bus Indianapolis to Buffalo: Trip Overview

Average Ticket PriceUS$115
Average Bus Trip Duration17h 45m
Number of daily buses5
Earliest bus departure12:20am
Distance699 km
Latest bus departure11:55pm

Indianapolis to Buffalo Bus

With Busbud, comparing and booking tickets for a bus from Indianapolis to Buffalo is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make it our job to connect you with the most dependable bus companies that cover bus service from Indianapolis to Buffalo.

Discover how much the bus trip from Indianapolis to Buffalo will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Indianapolis - Buffalo

  1. How long is the trip from Indianapolis to Buffalo by bus?

    The typical travel time from Indianapolis to Buffalo by bus is around 17h 45m. The fastest bus on this trip will get to Buffalo in 15h 50m

  2. What is the travel distance from Indianapolis to Buffalo?

    The distance covered from Indianapolis to Buffalo is 701 km (435 miles).

  3. What are the departure and arrival locations for buses traveling from Indianapolis to Buffalo?

    Buses traveling this route start their trip at Greyhound Amtrak Station, in Indianapolis, and end it at Buffalo Airport, in Buffalo.

  4. What is the cheapest way to go from Indianapolis to Buffalo?

    Taking the bus is the most budget-friendly option to travel from Indianapolis to Buffalo. With a starting ticket price of US$79, this bus becomes your top pick for this journey.

  5. How much does the bus ticket cost from Indianapolis to Buffalo?

    The bus fare from Indianapolis to Buffalo is approximately US$115.

  6. Is there an overnight bus from Indianapolis to Buffalo?

    Yes! Catch buses leaving from Indianapolis until 11:55pm and reaching Buffalo on the following day.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
05-16
No data
05-17
No data
Today
US$95
05-19
US$74
05-20
US$67
05-21
US$72
05-22
US$113
05-23
US$107
busbud logoThe cheapest trip from Indianapolis to Buffalo was searched and found on May 20, 2025 with a price of US$67

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Indianapolis to Buffalo, as early as possible.

You can expect to pay from US$67 to US$720 for a bus ticket from Indianapolis to Buffalo based on the last 2 days. You can expect to find the cheapest price for the trip at US$67 which is on 2025-05-20.

Usually Amtrak will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Indianapolis to Buffalo.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Indianapolis to Buffalo.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Indianapolis to Buffalo will emit less CO2 than a car or an airplane.

Tune out to the fine sounds of your best music playlist on your bus trip from Indianapolis to Buffalo while indulging in miles on end of beautiful scenic views.

Did you know?

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

What's the cheapest way to go from Indianapolis to Buffalo?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Indianapolis by bus?

Bus from Indianapolis to Buffalo

You can also go to Buffalo by train

Train from Indianapolis to Buffalo

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