How much is the bus ticket from Indianapolis to Buffalo?

The cheapest bus tickets from Indianapolis to Buffalo start from $95. The average price for this route is around $150. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the bus ride from Indianapolis to Buffalo?

The average bus trip duration from Indianapolis to Buffalo is 16h 30m, covering a distance of 434 miles (700 km). The quickest bus can get you there in 16h 25m and is operated by Greyhound .

Which bus companies service the Indianapolis to Buffalo route?

Several major bus companies operate on this route with 5 buses available per day, including services from Greyhound , Amtrak .

What is the earliest and latest departure time for the bus from Indianapolis to Buffalo?

The earliest bus departs from Indianapolis to Buffalo at 12:15am. And the latest bus departs at 11:30pm.

What are the CO₂ emissions for the bus trip from Indianapolis to Buffalo?

A bus trip from Indianapolis to Buffalo generates an estimated 17.4954 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

What is the best bus company from Indianapolis to Buffalo?

According to Busbud customers, the highest-rated bus company on this route is Amtrak , with an average rating of 4.1 out of 5 stars based on 5801 reviews.

Which bus company has the best Wi-Fi from Indianapolis to Buffalo?

Based on reviews on Busbud, the bus company Amtrak has the best Wi-Fi rating with a score of 3.6.

Which bus company has the most timely service from Indianapolis to Buffalo?

According to Busbud traveler reviews, the most timely bus company on this route is Amtrak , with a punctuality rating of 3.8 out of 5 stars.

Which bus company has the cleanest buses from Indianapolis to Buffalo?

According to Busbud traveler reviews, the bus company with the cleanest buses on this route is Amtrak , with a cleanliness rating of 4.5 out of 5 stars.

Bus Indianapolis to Buffalo from $87 | Refundable Tickets

Previously seen trips

Next departures for Indianapolis to Buffalo on May 26
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location
Greyhound + FlixBus	Bus	2:50pm	Indianapolis Northeast	1d 1h	4:15pm	Niagara Frontier Transportation Authority
FlixBus + Greyhound	Bus	12:20am	Downtown Transit Center	15h 55m	4:15pm	Niagara Frontier Transportation Authority
FlixBus + Greyhound	Bus	3:15am	Downtown Transit Center	17h 45m	9:00pm	Niagara Frontier Transportation Authority
	Bus	8:10pm	Indianapolis Bus Station	20h 5m	4:15pm	Niagara Frontier Transportation Authority
Greyhound + FlixBus	Bus	11:30pm	Downtown Transit Center	16h 45m	4:15pm	Niagara Frontier Transportation Authority

Compare 2 ways to go from Indianapolis to Buffalo

We recommend taking the bus

Among the sustainable travel choices, the Bus stands out as a good way to reach Buffalo. The journey takes about 16 hours 30 minutes and with fares starting at just $95, it presents an excellent value for a comfortable ride.

5bus per day

16h 30mAverage Duration

434 milesDistance

17kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$95 - $223	Average Duration16h 30m	CO₂ emissions 17kg CO₂e
Train	Average Price$148 - $980	Average Duration1d 2h	CO₂ emissions 65kg CO₂e

Where are the popular stops in Indianapolis and Buffalo?

Stops in Indianapolis

A
Greyhound Amtrak Station
350 S Illinois St, Indianapolis, IN 46225
Visit page

Stops in Buffalo

A
Buffalo Airport
Visit page
B
Transportation Center
185 Ellicott St, Buffalo, NY 14203, USA
Visit page
C
Exchange Street Station
75 Exchange St, Buffalo, NY 14203, USA
Visit page

Compare companies

Greyhound

3.5/587,558 reviews

Staff3.6

Timeliness2.9

Cleanliness3.4

Wifi2.5

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

Greyhound Indianapolis Buffalo recent customer reviews

The ticket I bought made me change buses 4 times and stoped more times, but it was not clear when I bought, all that discomforting situation was surprising for me.

Constanza P.

August 4, 2019

Amtrak

4.1/55,808 reviews

Staff4.7

Timeliness3.8

Cleanliness4.5

Wifi3.6

US bus companies:FlixBus, Greyhound, Futura, Elite, Chihuahuenses, Tufesa, Valley Transit

Frequently asked questions about traveling from Indianapolis to Buffalo, NY by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from Indianapolis to Buffalo?
The cheapest bus tickets from Indianapolis to Buffalo start from $95. The average price for this route is around $150. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Indianapolis to Buffalo?
The average bus trip duration from Indianapolis to Buffalo is 16h 30m, covering a distance of 434 miles (700 km). The quickest bus can get you there in 16h 25m and is operated by Greyhound.
Which bus companies service the Indianapolis to Buffalo route?
Several major bus companies operate on this route with 5 buses available per day, including services from Greyhound, Amtrak.
What is the earliest and latest departure time for the bus from Indianapolis to Buffalo?
The earliest bus departs from Indianapolis to Buffalo at 12:15am. And the latest bus departs at 11:30pm.
What are the CO₂ emissions for the bus trip from Indianapolis to Buffalo?
A bus trip from Indianapolis to Buffalo generates an estimated 17.4954 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Indianapolis to Buffalo?
According to Busbud customers, the highest-rated bus company on this route is Amtrak, with an average rating of 4.1 out of 5 stars based on 5801 reviews.
Which bus company has the best Wi-Fi from Indianapolis to Buffalo?
Based on reviews on Busbud, the bus company Amtrak has the best Wi-Fi rating with a score of 3.6.
Which bus company has the most timely service from Indianapolis to Buffalo?
According to Busbud traveler reviews, the most timely bus company on this route is Amtrak, with a punctuality rating of 3.8 out of 5 stars.
Which bus company has the cleanest buses from Indianapolis to Buffalo?
According to Busbud traveler reviews, the bus company with the cleanest buses on this route is Amtrak, with a cleanliness rating of 4.5 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

05/23

No data

05/24

No data

Today

$106

05/26

No data

05/27

$87

05/28

No data

05/29

No data

05/30

$97

The cheapest trip from Indianapolis to Buffalo, NY was searched and found on May 27, 2026 with a price of $87

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Indianapolis to Buffalo, NY, as early as possible.

You can expect to pay from $87 to $646 for a bus ticket from Indianapolis to Buffalo, NY based on the last 2 days. You can expect to find the cheapest price for the trip at $87 which is on 2026-05-27.

Usually Amtrak will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.