Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Isernia | Rome Tiburtina Bus Station | CheapestFastest | ||||
| Bus | Isernia | Rome Fiumicino Airport | No tags | ||||
| Bus | Isernia | Rome Fiumicino Airport | No tags | ||||
| Bus | Isernia | Rome Tiburtina Bus Station | No tags |
Last refresh of the prices: Last Sunday at 4:11 PM CET.
Compare 3 ways to go from Isernia to Rome
Among the sustainable travel choices, the carpool stands out as a good way to reach Rome. The journey takes about 2 hours, and with fares starting at just $15, it presents an excellent value for a comfortable ride.
Compare bus companies
Based on 11367 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. FlixBus ticket prices on this trip start at $19
Where are the popular stops in Isernia and Rome?
Frequently asked questions about travelling from Isernia to Rome by bus
What is the travel distance from Isernia to Rome?
The distance between Isernia and Rome is around 150 km (93 miles).
What are the departure and arrival locations for buses traveling from Isernia to Rome?
Buses traveling this route start their trip at Isernia, in Isernia, and end it at Rome Tiburtina Bus Station, in Rome.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Isernia to Rome was searched and found on Nov 18, 2025 with a price of $23To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Isernia to Rome, as early as possible.
You can expect to pay from $23 to $102 for a bus ticket from Isernia to Rome based on the last 2 days. You can expect to find the cheapest price for the trip at $23 which is on 2025-11-24.
