Bus Tickets from Jacksonville, FL to San Diego, CA, US

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TodayJul 15
TomorrowJul 16
from US$463
ThuJul 17
FriJul 18
SatJul 19
SunJul 20
MonJul 21
TueJul 22

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: July 16 at
    Departure city: Jacksonville
    Departure location: Jacksonville Bus Station
    Arrival time: July 19 at
    Destination city: San Diego
    Destination location: Greyhound Bus Stop
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: July 16 at
    Departure city: Jacksonville
    Departure location: Jacksonville Bus Station
    Arrival time: July 18 at
    Destination city: San Diego
    Destination location: Greyhound Bus Stop
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: July 16 at
    Departure city: Jacksonville
    Departure location: Jacksonville Bus Station
    Arrival time: July 18 at
    Destination city: San Diego
    Destination location: San Diego (Old Town-FlixBus)
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • Departure time: July 16 at
    Departure city: Jacksonville
    Departure location: Jacksonville Bus Station
    Arrival time: July 18 at
    Destination city: San Diego
    Destination location: Greyhound Bus Stop
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: July 16 at
    Departure city: Jacksonville
    Departure location: Jacksonville Bus Station
    Arrival time: July 19 at
    Destination city: San Diego
    Destination location: San Diego (Old Town-FlixBus)
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:

Last refresh of the prices: Today at 2:19 PM EDT.

Prices and availability are subject to change.

Accepted payments

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Compare 2 ways to go from Jacksonville to San Diego

Average PriceUS$388 - US$431Average Duration2d 14h
84kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Average PriceUS$571 - US$706Average Duration3d 22h
305kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Jacksonville to San Diego

Among the sustainable travel choices, the bus stands out as a good way to reach San Diego. The journey takes about 2 days, 14 hours 50 minutes, and with fares starting at just US$388, it presents an excellent value for a comfortable ride.

9bus per day
2d 14hAverage Duration
US$388Cheapest ticket
84kgCO₂ emissions

Bus Jacksonville to San Diego: Trip Overview

Average Ticket PriceUS$397
Average Bus Trip Duration2d 14h
Number of daily buses9
Earliest bus departure9:05am
Distance3363 km
Latest bus departure9:25pm

Jacksonville to San Diego Bus

Busbud helps you find a bus from Jacksonville to San Diego. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make sure you can find a bus service from Jacksonville to San Diego from the most reliable bus companies operating this trip.

Discover how much the bus trip from Jacksonville to San Diego will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Jacksonville, FL - San Diego, CA, US

  1. How far is Jacksonville from San Diego?

    The distance covered from Jacksonville to San Diego is 3364 km (2086 miles).

  2. What are the departure and arrival locations for buses traveling from Jacksonville to San Diego?

    Buses traveling this route start their trip at Jacksonville Amtrak Station, in Jacksonville, and end it at Mission Valley Sheraton, in San Diego.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
07-13
No data
07-14
US$129
Today
No data
07-16
US$479
07-17
No data
07-18
No data
07-19
No data
07-20
No data
busbud logoThe cheapest trip from Jacksonville to San Diego was searched and found on Jul 14, 2025 with a price of US$129

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Jacksonville to San Diego, as early as possible.

You can expect to pay from US$129 to US$479 for a bus ticket from Jacksonville to San Diego based on the last 2 days. You can expect to find the cheapest price for the trip at US$479 which is on 2025-07-16.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Jacksonville and San Diego!

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Jacksonville to San Diego, get comfy and count the stars.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Jacksonville to San Diego will emit less CO2 than a car or an airplane.

Tune out to the fine sounds of your best music playlist on your bus trip from Jacksonville to San Diego while indulging in miles on end of beautiful scenic views.

Did you know?

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

What's the cheapest way to go from Jacksonville to San Diego?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Jacksonville by bus?

Bus from Jacksonville to San Diego

You can also go to San Diego, CA, US by train

Train from Jacksonville, FL to San Diego, CA, US

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

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