How much is the bus ticket from Jacksonville to San Diego?

The cheapest bus tickets from Jacksonville to San Diego start from $238. The average price for this route is around $530. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the bus ride from Jacksonville to San Diego?

The average bus travel time from Jacksonville to San Diego is 2d 15h, covering a distance of 3362 km. The quickest bus can get you there in 2d 11h and is operated by Greyhound .

Which bus companies service the Jacksonville to San Diego route?

Several major bus companies operate on this route with 12 buses available per day, including services from Greyhound , FlixBus .

What are the earliest and latest departure times for the bus from Jacksonville to San Diego?

The earliest bus departs from Jacksonville to San Diego at 9:05am. And the latest bus departs at 10:05pm.

What are the CO₂ emissions for the bus trip from Jacksonville to San Diego?

A bus trip from Jacksonville to San Diego generates an estimated 84 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.

What is the best bus company from Jacksonville to San Diego?

According to Busbud customers, the highest-rated bus company on this route is Greyhound , with an average rating of 3.5 out of 5 stars based on 87387 reviews.

Which bus company has the best Wi-Fi from Jacksonville to San Diego?

Based on Busbud reviews, the bus company FlixBus has the highest Wi-Fi rating with a score of 2.7.

Which bus company has the best on-time performance from Jacksonville to San Diego?

According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus , with a punctuality rating of 3.9 out of 5 stars.

Which bus company has the cleanest buses from Jacksonville to San Diego?

According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus , with a cleanliness rating of 4.1 out of 5 stars.

Bus Jacksonville to San Diego from $429 | Refundable Tickets

Next bus departures

Next departures for Jacksonville to San Diego on December 3
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound Lines, Inc.	Bus	10:05pm	Jacksonville Bus Station	3d 3h	10:15pm	Downtown SD (Seaport)	Cheapest
	Bus	9:30am	Jacksonville Bus Station	2d 11h	5:45pm	Greyhound Bus Stop	Fastest
FlixBus + Greyhound Lines, Inc.	Bus	9:25pm	Jacksonville Bus Station	2d 19h	2:10pm	San Diego (Old Town-FlixBus)	No tags
Greyhound Lines, Inc. + FlixBus	Bus	9:30am	Jacksonville Bus Station	2d 15h	9:45pm	UCSD Health La Jolla Station	No tags
FlixBus + Greyhound Lines, Inc.	Bus	9:25pm	Jacksonville Bus Station	2d 15h	9:40am	UCSD Health La Jolla Station	No tags

Next departures for Jacksonville to San Diego on December 4
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound Lines, Inc. + FlixBus	Bus	9:30am	Jacksonville Bus Station	2d 15h	9:45pm	UCSD Health La Jolla Station	Cheapest
	Bus	9:30am	Jacksonville Bus Station	2d 11h	5:45pm	Greyhound Bus Stop	Fastest
FlixBus + Greyhound Lines, Inc.	Bus	9:05am	Jacksonville Bus Station	2d 12h	6:10pm	San Diego (Old Town-FlixBus)	No tags
FlixBus + Greyhound Lines, Inc.	Bus	9:25pm	Jacksonville Bus Station	2d 19h	2:10pm	San Diego (Old Town-FlixBus)	No tags
FlixBus + Greyhound Lines, Inc.	Bus	9:05am	Jacksonville Bus Station	2d 11h	5:35pm	UCSD Health La Jolla Station	No tags

Next departures for Jacksonville to San Diego on December 5
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound Lines, Inc.	Bus	10:05pm	Jacksonville Bus Station	3d 3h	10:15pm	Downtown SD (Seaport)	Cheapest
	Bus	9:30am	Jacksonville Bus Station	2d 11h	5:45pm	Greyhound Bus Stop	Fastest
FlixBus + Greyhound Lines, Inc.	Bus	9:05am	Jacksonville Bus Station	2d 12h	6:10pm	San Diego (Old Town-FlixBus)	No tags
FlixBus + Greyhound Lines, Inc.	Bus	9:25pm	Jacksonville Bus Station	2d 19h	2:10pm	San Diego (Old Town-FlixBus)	No tags
FlixBus + Greyhound Lines, Inc.	Bus	9:05am	Jacksonville Bus Station	2d 11h	5:35pm	UCSD Health La Jolla Station	No tags

Next departures for Jacksonville to San Diego on December 6
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound Lines, Inc. + FlixBus	Bus	9:30am	Jacksonville Bus Station	2d 15h	10:15pm	Downtown SD (Seaport)	Cheapest
	Bus	9:30am	Jacksonville Bus Station	2d 11h	5:45pm	Greyhound Bus Stop	Fastest
FlixBus + Greyhound Lines, Inc.	Bus	9:05am	Jacksonville Bus Station	2d 12h	6:10pm	San Diego (Old Town-FlixBus)	No tags
FlixBus + Greyhound Lines, Inc.	Bus	9:05am	Jacksonville Bus Station	2d 11h	5:35pm	UCSD Health La Jolla Station	No tags
Greyhound Lines, Inc. + FlixBus	Bus	9:30am	Jacksonville Bus Station	2d 15h	9:45pm	UCSD Health La Jolla Station	No tags

Next departures for Jacksonville to San Diego on December 7
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound Lines, Inc.	Bus	10:05pm	Jacksonville Bus Station	3d 3h	10:15pm	Downtown SD (Seaport)	Cheapest
	Bus	9:30am	Jacksonville Bus Station	2d 11h	5:45pm	Greyhound Bus Stop	Fastest
FlixBus + Greyhound Lines, Inc.	Bus	9:05am	Jacksonville Bus Station	2d 12h	6:10pm	San Diego (Old Town-FlixBus)	No tags
FlixBus + Greyhound Lines, Inc.	Bus	9:05am	Jacksonville Bus Station	2d 11h	5:35pm	UCSD Health La Jolla Station	No tags
Greyhound Lines, Inc. + FlixBus	Bus	9:30am	Jacksonville Bus Station	2d 15h	9:45pm	UCSD Health La Jolla Station	No tags

Next departures for Jacksonville to San Diego on December 8
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound Lines, Inc. + FlixBus	Bus	9:30am	Jacksonville Bus Station	2d 15h	9:45pm	UCSD Health La Jolla Station	Cheapest
FlixBus + Greyhound Lines, Inc.	Bus	9:05am	Jacksonville Bus Station	2d 11h	5:35pm	UCSD Health La Jolla Station	Fastest
FlixBus + Greyhound Lines, Inc.	Bus	9:05am	Jacksonville Bus Station	2d 12h	6:10pm	San Diego (Old Town-FlixBus)	No tags
	Bus	9:30am	Jacksonville Bus Station	2d 17h	11:50pm	Greyhound Bus Stop	No tags
FlixBus + Greyhound Lines, Inc.	Bus	9:25pm	Jacksonville Bus Station	2d 19h	2:10pm	San Diego (Old Town-FlixBus)	No tags

Last refresh of the prices: Last Sunday at 3:23 AM EST.

Compare 2 ways to go from Jacksonville to San Diego

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as a good way to reach San Diego. The journey takes about 2 days, 15 hours 40 minutes, and with fares starting at just $238, it presents an excellent value for a comfortable ride.

12bus per day

2d 15hAverage Duration

3362 kmDistance

84kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$238 - $1,038	Average Duration2d 15h	CO₂ emissions 84kg CO₂e
Train	Average Price$875 - $877	Average Duration3d 22h	CO₂ emissions 305kg CO₂e

Where are the popular stops in Jacksonville and San Diego?

Stops in Jacksonville

A
W Forsyth St
1111 W Forsyth St, Jacksonville, FL 32204, USA
B
Jacksonville Amtrak Station
3570 Clifford Ln, Jacksonville, FL 32209, USA
Visit page
C
Kings Avenue Station
1003 Kings Avenue, Jacksonville, FL 32207
D
JRTC Greyhound Bus Station
111 W. Forsyth St, Jacksonville, FL 32202, USA

Stops in San Diego

A
Mission Valley Sheraton
1433 Camino del Rio S, San Diego, CA 92108, USA
B
Old Town Courtyard Marriot
2435 Jefferson St, San Diego, CA 92110, USA
C
Downtown Holiday Inn
1617 1st Ave, San Diego, CA 92101, USA
D
Greyhound Station
1313 National Ave, San Diego, CA 92101, USA
E
Market St. & Park Blvd
601 Park Boulevard, San Diego, CA 92101, USA
F
San Ysidro McDonald's
727 E San Ysidro Blvd, San Diego, CA 92173, USA

Compare bus companies

Greyhound

3.5/587,412 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

FlixBus

3.5/511,504 reviews

Staff4.2

Timeliness3.9

Cleanliness4.1

Wifi2.7

US Bus Companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Big Sky

Frequently asked questions about travelling from Jacksonville, FL to San Diego, CA, US by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from Jacksonville to San Diego?
The cheapest bus tickets from Jacksonville to San Diego start from $238. The average price for this route is around $530. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Jacksonville to San Diego?
The average bus travel time from Jacksonville to San Diego is 2d 15h, covering a distance of 3362 km. The quickest bus can get you there in 2d 11h and is operated by Greyhound.
Which bus companies service the Jacksonville to San Diego route?
Several major bus companies operate on this route with 12 buses available per day, including services from Greyhound, FlixBus.
What are the earliest and latest departure times for the bus from Jacksonville to San Diego?
The earliest bus departs from Jacksonville to San Diego at 9:05am. And the latest bus departs at 10:05pm.
What are the CO₂ emissions for the bus trip from Jacksonville to San Diego?
A bus trip from Jacksonville to San Diego generates an estimated 84 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Jacksonville to San Diego?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87387 reviews.
Which bus company has the best Wi-Fi from Jacksonville to San Diego?
Based on Busbud reviews, the bus company FlixBus has the highest Wi-Fi rating with a score of 2.7.
Which bus company has the best on-time performance from Jacksonville to San Diego?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Jacksonville to San Diego?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

12-01

$865

12-02

$488

Today

$573

12-04

$497

12-05

$457

12-06

$492

12-07

$429

12-08

$460

The cheapest trip from Jacksonville, FL to San Diego, CA, US was searched and found on Dec 7, 2025 with a price of $429

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Jacksonville, FL to San Diego, CA, US, as early as possible.

You can expect to pay from $429 to $865 for a bus ticket from Jacksonville, FL to San Diego, CA, US based on the last 2 days. You can expect to find the cheapest price for the trip at $429 which is on 2025-12-07.