Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Knoxville Bus Station | Cincinnati Bus Station | CheapestFastest |
Last refresh of the prices: Last Monday at 6:15 PM EST.
Get from Knoxville to Cincinnati
The journey takes about 5 hours 25 minutes, and with fares starting at just $61, it presents an excellent value for a comfortable ride.
Where are the popular stops in Knoxville and Cincinnati?
Stops in Knoxville
- AKnoxville Area Transit Bus Stop, 100 Kirkwood St, Knoxville, TN 37914, USA
Stops in Cincinnati
- A1005 Gilbert Ave, Cincinnati, OH 45202
- B
Northland Blvd
290-322 Northland Blvd, Springdale, OH 45246, USA
Compare bus companies
Based on 87415 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. Greyhound ticket prices on this trip start at $61
Greyhound Knoxville Cincinnati recent customer reviews
Very nice trip
Paula L.
Frequently asked questions about travelling from Knoxville, TN to Cincinnati by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Knoxville to Cincinnati?
The cheapest bus tickets from Knoxville to Cincinnati start from $61. The average price for this route is around $68. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Knoxville to Cincinnati?
The average bus travel time from Knoxville to Cincinnati is 5h 25m, covering a distance of 362 km. The quickest bus can get you there in 5h 25m and is operated by Greyhound.
Which bus companies service the Knoxville to Cincinnati route?
Several major bus companies operate on this route with 1 buses available per day.
What are the earliest and latest departure times for the bus from Knoxville to Cincinnati?
The earliest bus departs from Knoxville to Cincinnati at 10:00pm. And the latest bus departs at 10:00pm.
What are the CO₂ emissions for the bus trip from Knoxville to Cincinnati?
A bus trip from Knoxville to Cincinnati generates an estimated 9 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Knoxville, TN to Cincinnati was searched and found on Dec 4, 2025 with a price of $51To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Knoxville, TN to Cincinnati, as early as possible.
You can expect to pay from $51 to $71 for a bus ticket from Knoxville, TN to Cincinnati based on the last 2 days. You can expect to find the cheapest price for the trip at $51 which is on 2025-12-06.
