Bus Tickets from Lexington, KY to St. Louis

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TodaySep 2
from US$94
TomorrowSep 3
ThuSep 4
from US$70
FriSep 5
SatSep 6
from US$71
SunSep 7
MonSep 8
from US$71
TueSep 9

Cheap buses leaving Thursday

One passenger / one way

  • This trip is recommended because it is the: Cheapest + Fastest
    Departure time: September 4 at
    Departure city: Lexington
    Departure location: WJW Investments Bus Stop
    Arrival time: September 4 at
    Destination city: St. Louis
    Destination location: Gateway Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:

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Bus Lexington, KY to St. Louis: Trip Overview

Average Ticket PriceUS$71
Average Bus Trip Duration9h 50m
Number of daily buses1
Earliest bus departure2:45pm
Distance503 km

Lexington to St. Louis Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Lexington to St. Louis.

Bus service from Lexington to St. Louis will be provided by the most trusted bus companies.

Whether it is cheap bus tickets or more luxurious buses going to St. Louis from Lexington, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Lexington, KY - St. Louis

  1. How far is Lexington from St. Louis?

    Lexington and St. Louis are 504 km (313 miles) apart.

  2. What are the departure and arrival locations for buses traveling from Lexington to St. Louis?

    Buses departing from WJW Investments Bus Stop in Lexington will take you to Gateway Station in St. Louis.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
08-31
US$71
09-01
US$109
Today
US$86
09-03
US$58
09-04
US$63
09-05
No data
09-06
US$64
09-07
No data
busbud logoThe cheapest trip from Lexington, KY to St. Louis was searched and found on Sep 3, 2025 with a price of US$58

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Lexington, KY to St. Louis, as early as possible.

You can expect to pay from US$58 to US$109 for a bus ticket from Lexington, KY to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at US$58 which is on 2025-09-03.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Lexington to St. Louis but it'll also be endearing to native speakers who will surely appreciate your effort.

Much more than a mere vehicle taking you from Lexington to St. Louis, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Lexington to St. Louis.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Lexington to St. Louis.

Did you know?

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

Will you be returning to Lexington, KY by bus?

Bus from St. Louis to Lexington, KY

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