Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Mainz | Brussels North Train Station | CheapestFastest | ||||
| Bus | Mainz | Brussels North Train Station | No tags | ||||
| Bus | Mainz | Brussels Airport BRU | No tags |
Last refresh of the prices: Today at 4:45 PM CEST.
Compare 2 ways to go from Mainz to Brussels
Among the sustainable travel choices, the Train stands out as a good way to reach Brussels. The journey takes about 4 hours 18 minutes, and with fares starting at just PLN 312, it presents an excellent value for a comfortable ride.
Where are the popular stops in Mainz and Brussels?
Stops in Mainz
- A
Mainz
Hechtsheimer Str. 65, 55131 Mainz, Germany - B
Mainz- Kaiser-Wilhelm-Ring 16- gegenüberliegende Straßenseite
Kaiser-Wilhelm-Ring 16 (gegenüberliegende Straßenseite), 55118 Mainz
Stops in Brussels
- ARue de France 85, 1060 Saint-Gilles, Belgium
- BBoulevard Simon Bolivar 7, 1030 Schaerbeek, Belgium
- C
Centrale
Rue de Loxum 5, 1000 Bruxelles, Belgium - DPachecolaan 5, 1000 Brussel, Belgium
Compare bus companies
Based on 12647 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi‑Fi. FlixBus ticket prices on this trip start at PLN 102
Frequently asked questions about travelling from Mainz to Brussels by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Mainz to Brussels?
The cheapest bus tickets from Mainz to Brussels start from PLN 102. The average price for this route is around PLN 222. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Mainz to Brussels?
The average bus travel time from Mainz to Brussels is 12h 50m, covering a distance of 289 km. The quickest bus can get you there in 5h 45m and is operated by FlixBus.
Which bus companies service the Mainz to Brussels route?
Several major bus companies operate on this route with 1 buses available per day.
What are the earliest and latest departure times for the bus from Mainz to Brussels?
The earliest bus departs from Mainz to Brussels at 12:20pm. And the latest bus departs at 12:20pm.
What are the CO₂ emissions for the bus trip from Mainz to Brussels?
A bus trip from Mainz to Brussels generates an estimated 7.219975 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Mainz to Brussels was searched and found on May 15, 2026 with a price of PLN 153To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Mainz to Brussels, as early as possible.
You can expect to pay from PLN 153 to PLN 353 for a bus ticket from Mainz to Brussels based on the last 2 days. You can expect to find the cheapest price for the trip at PLN 192 which is on 2026-05-17.
