Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Manitowoc | San Ysidro Bus terminal | CheapestFastest |
Last refresh of the prices: Yesterday at 3:53 AM CST.
Get from Manitowoc to San Ysidro
The journey takes about 2 days, 18 hours 50 minutes, and with fares starting at just $320, it presents an excellent value for a comfortable ride.
Compare bus companies
Based on 87524 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi‑Fi. Greyhound ticket prices on this trip start at $320
Frequently asked questions about travelling from Manitowoc to San Ysidro, CA by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Manitowoc to San Ysidro?
The cheapest bus tickets from Manitowoc to San Ysidro start from $320. The average price for this route is around $324. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Manitowoc to San Ysidro?
The average bus travel time from Manitowoc to San Ysidro is 2d 18h, covering a distance of 2842 km. The quickest bus can get you there in 2d 20h and is operated by Greyhound.
Which bus companies service the Manitowoc to San Ysidro route?
Several major bus companies operate on this route with 1 buses available per day.
What are the earliest and latest departure times for the bus from Manitowoc to San Ysidro?
The earliest bus departs from Manitowoc to San Ysidro at 5:45pm. And the latest bus departs at 5:45pm.
What are the CO₂ emissions for the bus trip from Manitowoc to San Ysidro?
A bus trip from Manitowoc to San Ysidro generates an estimated 71 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Manitowoc to San Ysidro, CA was searched and found on Mar 2, 2026 with a price of $332To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Manitowoc to San Ysidro, CA, as early as possible.
You can expect to pay from $332 to $346 for a bus ticket from Manitowoc to San Ysidro, CA based on the last 2 days. You can expect to find the cheapest price for the trip at $332 which is on 2026-03-02.
