Bus Tickets from Milano to Syracuse

Next departures

Next departures for Milano to Syracuse on October 13
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Flixbus
Milan (San Donato M3)
Terminal InterbusCheapest
Flixbus
Lampugnano bus station
Terminal InterbusFastest
Flixbus
Lampugnano bus station
Terminal InterbusNo tags
Flixbus
Milan (Assago M2)
Terminal InterbusNo tags
Flixbus
Via Luigi Cadorna
Terminal InterbusNo tags

Last refresh of the prices: Last Tuesday at 5:38 AM CEST.

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Compare 3 ways to go from Milano to Syracuse

Bus
Average PriceUS$52 - US$186Average Duration1d 3h
27kg CO₂e5 out of 5 stars
Cheapest
Train
Average PriceUS$305 - US$305Average Duration22h 41m
26kg CO₂e5 out of 5 stars
Most eco-friendly
Carpool
Average PriceUS$120 - US$120Average Duration15h 40m
45kg CO₂e4 out of 5 stars
Fastest
busbud logoBusbud recommends taking the bus from Milano to Syracuse

Among the sustainable travel choices, the bus stands out as a good way to reach Syracuse. The journey takes about 1 day, 3 hours 10 minutes, and with fares starting at just US$52, it presents an excellent value for a comfortable ride.

6bus per day
1d 3hAverage Duration
US$52Cheapest ticket
27kgCO₂ emissions

Bus Milano to Syracuse: Trip Overview

Average Ticket PriceUS$84
Average Bus Trip Duration1d 3h
Number of daily buses6
Earliest bus departure12:55pm
Distance1071 km
Latest bus departure9:30pm

Milano to Syracuse Bus

With Busbud, comparing and booking tickets for a bus from Milano to Syracuse is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make it our job to connect you with the most dependable bus companies that cover bus service from Milano to Syracuse.

Discover how much the bus trip from Milano to Syracuse will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Milano - Syracuse

  1. What is the travel distance from Milano to Syracuse?

    Milano and Syracuse are 1064 km (660 miles) apart.

  2. What are the departure and arrival locations for buses traveling from Milano to Syracuse?

    Buses departing from Lampugnano in Milano will take you to Fermata dell'autobus Siracusa in Syracuse.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
10-07
US$68
10-08
US$66
Today
US$52
10-10
US$70
10-11
US$58
10-12
US$73
10-13
US$63
10-14
US$57
busbud logoThe cheapest trip from Milano to Syracuse was searched and found on Oct 9, 2025 with a price of US$52

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Milano to Syracuse, as early as possible.

You can expect to pay from US$52 to US$105 for a bus ticket from Milano to Syracuse based on the last 2 days. You can expect to find the cheapest price for the trip at US$57 which is on 2025-10-14.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Milano to Syracuse.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Milano to Syracuse.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Milano to Syracuse will emit less CO2 than a car or an airplane.

Make a music playlist for your bus ride from Milano to Syracuse, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

What's the cheapest way to go from Milano to Syracuse?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Milano by bus?

Bus from Syracuse to Milano

You can also go to Syracuse by train

Train from Milano to Syracuse

Why choose Busbud?

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