Bus from Milano to Syracuse: Tickets & Timetables

Previously seen journeys

Next departures from Milano to Syracuse on 2 December
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBusBus
Milan (Assago M2)
Terminal InterbusNo tags
FlixBusBus
Milan (Malpensa Aeroporto Terminal 1)
Terminal InterbusNo tags
FlixBusBus
Aeroporto Malpensa T2
Terminal InterbusNo tags
FlixBusBus
Lampugnano bus station
Terminal InterbusNo tags
FlixBusBus
Milan (San Donato M3)
Terminal InterbusNo tags

Compare 3 ways to travel from Milano to Syracuse

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as a good way to reach Syracuse. The journey takes about 1 day, 3 hours 10 minutes and with fares starting at just £44, it presents an excellent value for a comfortable ride.

6bus per day
1d 3hAverage duration
657 milesDistance
26kgCO₂ emissions
Average price£44 - £157Average duration1d 3h
26kg CO₂e
Average price£237 - £237Average duration22h 41m
26kg CO₂e
Carpool
Average price£93 - £93Average duration15h 40m
45kg CO₂e

Frequently asked questions about travelling by bus from Milano to Syracuse

Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.

  1. How much is the bus ticket from Milano to Syracuse?

    The cheapest coach tickets from Milano to Syracuse start from £44. The average price for this route is around £75. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

  2. How long is the bus journey from Milano to Syracuse?

    The average bus journey time from Milano to Syracuse is 1d 3h, covering a distance of 657 miles. The fastest bus can take you there in 20h 30m and is operated by FlixBus.

  3. Which bus companies service the Milano to Syracuse route?

    Several major bus companies operate on this route with 6 buses available per day.

  4. What is the earliest and latest departure time for the bus from Milano to Syracuse?

    The earliest bus departs from Milano to Syracuse at 11:50. And the latest bus departs at 21:30.

  5. What are the CO₂ emissions for the bus trip from Milano to Syracuse?

    A bus journey from Milano to Syracuse produces an estimated 26 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
30/11
£65
01/12
£47
Today
£44
03/12
£42
04/12
£57
05/12
£76
06/12
£67
07/12
£73
busbud logoThe cheapest trip from Milano to Syracuse was searched and found on 3 Dec 2025 with a price of £42

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Milano to Syracuse as early as possible.

You can expect to pay from £42 to £131 for a bus ticket from Milano to Syracuse based on the last 2 days. You can expect to find the cheapest price for the trip at £42, which is on 2025-12-03.

What's the cheapest way to go from Milano to Syracuse?

busbud logoThe bus is the cheapest travel choice for this destination

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