Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound | Bus | Milwaukee Mitchell MKE Airport | 4565 Gaynor Ave, North Charleston | No tags | ||||
Greyhound + FlixBus | Bus | Milwaukee Mitchell MKE Airport | 4565 Gaynor Ave, North Charleston | No tags | ||||
Greyhound + FlixBus | Bus | Milwaukee Bus Station, St. Paul & N6th road. | 4565 Gaynor Ave, North Charleston | No tags | ||||
FlixBus + Greyhound | Bus | Milwaukee Bus Station, St. Paul & N6th road. | 4565 Gaynor Ave, North Charleston | No tags | ||||
FlixBus + Greyhound | Bus | Goerke's Corners Park & Ride (Brookfield) | 4565 Gaynor Ave, North Charleston | No tags |
Compare 2 ways to go from Milwaukee to Charleston
Among the sustainable travel choices, the Bus stands out as a good way to reach Charleston. The journey takes about 1 day, 21 hours 35 minutes, and with fares starting at just $255, it presents an excellent value for a comfortable ride.
Where are the popular stops in Milwaukee and Charleston?
Stops in Milwaukee
- B433 W St Paul Ave, Milwaukee, WI 53203, USA
- C
S Cesar Chavez
1016 S Cesar E Chavez Dr, Milwaukee, WI 53204, USA
Compare bus companies
Frequently asked questions about travelling from Milwaukee to Charleston, SC, US by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Milwaukee to Charleston?
The cheapest bus tickets from Milwaukee to Charleston start from $255. The average price for this route is around $271. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Milwaukee to Charleston?
The average bus travel time from Milwaukee to Charleston is 1d 21h, covering a distance of 1325 km. The quickest bus can get you there in 1d 3h and is operated by FlixBus.
Which bus companies service the Milwaukee to Charleston route?
What are the earliest and latest departure times for the bus from Milwaukee to Charleston?
The earliest bus departs from Milwaukee to Charleston at 9:00am. And the latest bus departs at 7:55pm.
What are the CO₂ emissions for the bus trip from Milwaukee to Charleston?
A bus trip from Milwaukee to Charleston generates an estimated 33 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Milwaukee to Charleston?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87500 reviews.
Which bus company has the best Wi-Fi from Milwaukee to Charleston?
Based on Busbud reviews, the bus company FlixBus has the highest Wi-Fi rating with a score of 2.7.
Which bus company has the best on-time performance from Milwaukee to Charleston?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Milwaukee to Charleston?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Milwaukee to Charleston, SC, US was searched and found on Jan 17, 2026 with a price of $261To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Milwaukee to Charleston, SC, US, as early as possible.
You can expect to pay from $261 to $261 for a bus ticket from Milwaukee to Charleston, SC, US based on the last 2 days. You can expect to find the cheapest price for the trip at $261 which is on 2026-01-17.
What's the cheapest way to go from Milwaukee to Charleston, SC, US?
The Bus is the cheapest travel choice for this destination
