Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Greyhound Station | Opelika (4th Street Station) | No tags | ||||
| Bus | Greyhound Station | Opelika (4th Street Station) | No tags | ||||
| Bus | Greyhound Station | Opelika (4th Street Station) | No tags | ||||
| Bus | Greyhound Station | Opelika (4th Street Station) | No tags | ||||
| Bus | Greyhound Station | Opelika (4th Street Station) | No tags |
Get from Mobile to Opelika
The journey takes about 4 hours 25 minutes, and with fares starting at just $64, it presents an excellent value for a comfortable ride.
Where are the popular stops in Mobile and Opelika?
Stops in Opelika
- A
McDonald's - Opelika
1104 Columbus Pkwy, Opelika, AL 36801, USA
Compare bus companies
Based on 87388 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. Greyhound ticket prices on this trip start at $64
Frequently asked questions about travelling from Mobile to Opelika by bus
How far is Mobile from Opelika?
The distance between Mobile and Opelika is approximately 334 km (207 miles).
What are the departure and arrival locations for buses traveling from Mobile to Opelika?
Buses departing from Greyhound Station in Mobile will take you to McDonald's - Opelika in Opelika.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Mobile to Opelika was searched and found on Nov 19, 2025 with a price of $83To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Mobile to Opelika, as early as possible.
