Bus Tickets from New Orleans to Tupelo

Find affordable bus tickets from New Orleans to Tupelo with flexible options. Book your trip now

Join 75M+ travelers booking 2M+ routes across 85+ countries.
Enjoy our 24/7 customer service to assist you at every step.
Cancel anytime and receive a 100% refund, no reason needed.
TodayJun 11
TomorrowJun 12
from US$169
FriJun 13
SatJun 14
SunJun 15
MonJun 16
TueJun 17
WedJun 18

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: June 12 at
    Departure city: New Orleans
    Departure location: New Orleans Bus Station
    Arrival time: June 12 at
    Destination city: Tupelo
    Destination location: Tupelo (Brothers Quick Stop)
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: June 12 at
    Departure city: New Orleans
    Departure location: New Orleans Bus Station
    Arrival time: June 13 at
    Destination city: Tupelo
    Destination location: Tupelo (Brothers Quick Stop)
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: June 12 at
    Departure city: New Orleans
    Departure location: New Orleans Bus Station
    Arrival time: June 12 at
    Destination city: Tupelo
    Destination location: Tupelo (Brothers Quick Stop)
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: June 12 at
    Departure city: New Orleans
    Departure location: New Orleans Bus Station
    Arrival time: June 13 at
    Destination city: Tupelo
    Destination location: Tupelo (Brothers Quick Stop)
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: June 12 at
    Departure city: New Orleans
    Departure location: New Orleans Bus Station
    Arrival time: June 13 at
    Destination city: Tupelo
    Destination location: Tupelo (Brothers Quick Stop)
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:

Last refresh of the prices: Today at 1:07 PM CDT.

Prices and availability are subject to change.

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Bus New Orleans to Tupelo: Trip Overview

Average Ticket PriceUS$161
Average Bus Trip Duration15h 25m
Number of daily buses3
Earliest bus departure7:40am
Distance495 km
Latest bus departure11:35pm

New Orleans to Tupelo Bus

Busbud helps you find a bus from New Orleans to Tupelo. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make sure you can find a bus service from New Orleans to Tupelo from the most reliable bus companies operating this trip.

From cheap bus tickets to more luxurious buses travelling from New Orleans to Tupelo, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip New Orleans - Tupelo

  1. How long is the bus trip from New Orleans to Tupelo?

    The trip from New Orleans to Tupelo will take on average 15h 25m. For the shortest travel time, select the fastest bus available, which will take you to Tupelo in about 11h 5m.

  2. How far is New Orleans from Tupelo?

    The distance between New Orleans and Tupelo is around 495 km (307 miles).

  3. What is the cheapest way to travel from New Orleans to Tupelo?

    If you're on a budget, consider traveling by bus to Tupelo from New Orleans; it tends to be more affordable. Starting at US$147, this bus is the most cost-effective option for your journey.

  4. How much does it cost to take the bus from New Orleans to Tupelo?

    Taking the bus from New Orleans to Tupelo costs on average US$161.

  5. Can I take an overnight bus from New Orleans to Tupelo?

    Yes! Catch buses leaving from New Orleans until 11:35pm and reaching Tupelo on the following day.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
06-09
No data
06-10
No data
Today
No data
06-12
US$161
06-13
No data
06-14
No data
06-15
No data
06-16
No data
busbud logoThe cheapest trip from New Orleans to Tupelo was searched and found on Jun 12, 2025 with a price of US$161

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from New Orleans to Tupelo, as early as possible.

You can expect to pay from US$161 to US$161 for a bus ticket from New Orleans to Tupelo based on the last 2 days. You can expect to find the cheapest price for the trip at US$161 which is on 2025-06-12.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between New Orleans and Tupelo!

Start sightseeing the minute your bus leaves the station. If you're on the night bus from New Orleans to Tupelo, get comfy and count the stars.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from New Orleans to Tupelo that are otherwise impossible to come by with a plane.

Tune out to the fine sounds of your best music playlist on your bus trip from New Orleans to Tupelo while indulging in miles on end of beautiful scenic views.

Did you know?

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

Will you be returning to New Orleans by bus?

Bus from New Orleans to Tupelo

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud makes bus travel easy. We help travellers find a bus, plot routes, and book intercity bus tickets all over the world. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

People from around the world trust Busbud

‌

Popular Buses Connecting New Orleans

Buses Leaving from New Orleans

Buses Going to New Orleans

Popular Buses Connecting Tupelo

Buses Leaving from Tupelo

Buses Going to Tupelo