Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Opelika (4th Street Station) | Greyhound Station | Cheapest | ||||
| Bus | Opelika (4th Street Station) | Greyhound Station | Fastest | ||||
| Bus | Opelika (4th Street Station) | Greyhound Station | No tags |
Last refresh of the prices: Today at 8:47 AM CST.
Get from Opelika to Mobile
The journey takes about 4 hours 10 minutes, and with fares starting at just $61, it presents an excellent value for a comfortable ride.
Where are the popular stops in Opelika and Mobile?
Stops in Opelika
- A
McDonald's - Opelika
1104 Columbus Pkwy, Opelika, AL 36801, USA
Compare bus companies
Based on 87397 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. Greyhound ticket prices on this trip start at $61
Frequently asked questions about travelling from Opelika to Mobile by bus
What is the travel distance from Opelika to Mobile?
It's about 334 km (207 miles) from Opelika to Mobile.
What are the departure and arrival locations for buses traveling from Opelika to Mobile?
Buses departing from McDonald's - Opelika in Opelika will take you to Greyhound Station in Mobile.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Opelika to Mobile was searched and found on Nov 27, 2025 with a price of $75To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Opelika to Mobile, as early as possible.
You can expect to pay from $75 to $83 for a bus ticket from Opelika to Mobile based on the last 2 days. You can expect to find the cheapest price for the trip at $75 which is on 2025-11-27.
