Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound Lines, Inc. + FlixBus | Bus | Panama City Beach Station | Philadelphia, 199 Spring Garden St | Cheapest | ||||
 | Bus | Panama City Beach Station | 199 Spring Garden St. | Fastest | ||||
| Bus | Panama City Beach Station | 199 Spring Garden St. | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Panama City Beach Station | 199 Spring Garden St. | No tags | ||||
| Bus | Panama City Beach Station | 199 Spring Garden St. | No tags |
Last refresh of the prices: Today at 9:29 AM CST.
Get from Panama City to Philadelphia
The journey takes about 1 day, 15 hours 30 minutes, and with fares starting at just $272, it presents an excellent value for a comfortable ride.
Where are the popular stops in Panama City and Philadelphia?
Stops in Panama City
- A
Panama City Greyhound Bus Station
917 Harrison Ave, Panama City, FL 32401
Stops in Philadelphia
- BOff of Race Street between 5th Street and, N 6th St, Philadelphia, PA 19106, USA
- C
#2842 St.Vincent St
15th St Trolley Station, Philadelphia, PA 19102, USA - D
Bus Station
1001 Filbert St, Philadelphia, PA 19107, USA - E
Island Av & Suffolk Av MBFS
3000 Island Ave, Philadelphia, PA 19153, USA - F
NRG SEPTA Station
3701 Broad St, Philadelphia, PA 19148, USA
Compare bus companies
Based on 87481 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. Greyhound ticket prices on this trip start at $297
Frequently asked questions about travelling from Panama City, US to Philadelphia, PA by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Panama City to Philadelphia?
The cheapest bus tickets from Panama City to Philadelphia start from $272. The average price for this route is around $332. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Panama City to Philadelphia?
The average bus travel time from Panama City to Philadelphia is 1d 15h, covering a distance of 1451 km. The quickest bus can get you there in 1d 6h and is operated by Greyhound.
Which bus companies service the Panama City to Philadelphia route?
Several major bus companies operate on this route with 20 buses available per day.
What are the earliest and latest departure times for the bus from Panama City to Philadelphia?
The earliest bus departs from Panama City to Philadelphia at 7:30am. And the latest bus departs at 9:40pm.
What are the CO₂ emissions for the bus trip from Panama City to Philadelphia?
A bus trip from Panama City to Philadelphia generates an estimated 36 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Panama City, US to Philadelphia, PA was searched and found on Jan 7, 2026 with a price of $244To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Panama City, US to Philadelphia, PA, as early as possible.
You can expect to pay from $244 to $356 for a bus ticket from Panama City, US to Philadelphia, PA based on the last 2 days. You can expect to find the cheapest price for the trip at $244 which is on 2026-01-07.
