Bus Tickets from Philadelphia, PA to Winston-Salem

SatAug 2
SunAug 3
MonAug 4
TueAug 5
from US$76
WedAug 6
from US$85
ThuAug 7
FriAug 8
SatAug 9

Cheap buses leaving Tuesday

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: August 5 at
    Departure city: Philadelphia
    Departure location: 199 Spring Garden St.
    Arrival time: August 6 at
    Destination city: Winston-Salem
    Destination location: Winston Salem Greyhound Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: August 5 at
    Departure city: Philadelphia
    Departure location: Philadelphia, 199 Spring Garden St
    Arrival time: August 6 at
    Destination city: Winston-Salem
    Destination location: Winston Salem Greyhound Bus Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: August 5 at
    Departure city: Philadelphia
    Departure location: 199 Spring Garden St.
    Arrival time: August 5 at
    Destination city: Winston-Salem
    Destination location: Winston Salem Greyhound Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: August 5 at
    Departure city: Philadelphia
    Departure location: Philadelphia, 199 Spring Garden St
    Arrival time: August 5 at
    Destination city: Winston-Salem
    Destination location: Winston Salem Greyhound Bus Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: August 5 at
    Departure city: Philadelphia
    Departure location: 199 Spring Garden St.
    Arrival time: August 6 at
    Destination city: Winston-Salem
    Destination location: Winston Salem Greyhound Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:

Last refresh of the prices: Last Tuesday at 3:19 PM EDT.

Prices and availability are subject to change.

Accepted payments

  • Visa
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  • American Express
  • China Union Pay
  • Diners Club Canada
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  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Compare 2 ways to go from Philadelphia to Winston-Salem

Bus
Average PriceUS$75 - US$227Average Duration16h 40m
15kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Train
Average PriceUS$107 - US$200Average Duration11h 39m
56kg CO₂e1 out of 5 stars
Fastest
busbud logoBusbud recommends taking the train from Philadelphia to Winston-Salem

Among the sustainable travel choices, the train stands out as a good way to reach Winston-Salem. The journey takes about 11 hours 39 minutes, and with fares starting at just US$107, it presents an excellent value for a comfortable ride.

2train per day
11h 39mAverage Duration
US$107Cheapest ticket
56kgCO₂ emissions

Bus Philadelphia, PA to Winston-Salem: Trip Overview

Average Ticket PriceUS$112
Average Bus Trip Duration16h 40m
Number of daily buses15
Earliest bus departure12:50am
Distance620 km
Latest bus departure10:30pm

Philadelphia to Winston-Salem Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Philadelphia to Winston-Salem.

Bus service from Philadelphia to Winston-Salem will be provided by the most trusted bus companies.

Discover how much the bus trip from Philadelphia to Winston-Salem will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Philadelphia, PA - Winston-Salem

  1. How far is Philadelphia from Winston-Salem?

    It's about 619 km (384 miles) from Philadelphia to Winston-Salem.

  2. What are the departure and arrival locations for buses traveling from Philadelphia to Winston-Salem?

    Buses departing from Philadelphia Airport in Philadelphia will take you to Winston Salem Greyhound Bus Station in Winston-Salem.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
07-29
US$95
07-30
US$82
Today
US$90
08-01
US$108
08-02
US$84
08-03
US$77
08-04
US$68
08-05
US$68
busbud logoThe cheapest trip from Philadelphia, PA to Winston-Salem was searched and found on Aug 4, 2025 with a price of US$68

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Philadelphia, PA to Winston-Salem, as early as possible.

You can expect to pay from US$68 to US$221 for a bus ticket from Philadelphia, PA to Winston-Salem based on the last 2 days. You can expect to find the cheapest price for the trip at US$68 which is on 2025-08-04.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Philadelphia to Winston-Salem but it'll also be endearing to native speakers who will surely appreciate your effort.

Much more than a mere vehicle taking you from Philadelphia to Winston-Salem, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Philadelphia to Winston-Salem will emit less CO2 than a car or an airplane.

Make a music playlist for your bus ride from Philadelphia to Winston-Salem, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

What's the cheapest way to go from Philadelphia, PA to Winston-Salem?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Philadelphia, PA by bus?

Bus from Philadelphia, PA to Winston-Salem

You can also go to Winston-Salem by train

Train from Philadelphia, PA to Winston-Salem

Why choose Busbud?

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