Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Price and booking link |
|---|---|---|---|---|---|---|---|
 | Bus | Parcheggio Via Pietransantina | Terminal Bus Palermo | ||||
| Bus | Parcheggio Via Pietransantina | Terminal Bus Palermo | ||||
| Bus | park Aurelia | Terminal Bus Palermo | ||||
| Bus | Parcheggio Via Pietransantina | Terminal Bus Palermo | ||||
| Bus | Parcheggio Via Pietransantina | Terminal Bus Palermo |
Get from Pisa to Palermo
The journey takes about 21 hours 50 minutes, and with fares starting at just $131, it presents an excellent value for a comfortable ride.
Where are the popular stops in Pisa and Palermo?
Stops in Pisa
- AVia Pietrasantina, 56123 Pisa PI
- C
Piazza della Stazione
Piazza della Stazione, 1, 56125 Pisa PI, Italy
Stops in Palermo
- AVia Tommaso Fazello, 16, 90123 Palermo PA, Italy
- BPunta Raisi, 90145, Palermo
- CPiazza Cairoli, 8-14, 90123 Palermo, Italy
- D90143 Palermo PA, Italy
- E
Via Paolo Balsamo, 31
Via Paolo Balsamo, 23-31, 90123 Palermo, Italy - F
Piazza Ruggero Settimo, 12
Piazza Ruggero Settimo, 12C, 90139 Palermo, Italy
Compare bus companies
Based on 12771 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi‑Fi. FlixBus ticket prices on this trip start at $131
Frequently asked questions about travelling from Pisa to Palermo by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Pisa to Palermo?
The cheapest bus tickets from Pisa to Palermo start from $131. The average price for this route is around $182. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Pisa to Palermo?
The average bus travel time from Pisa to Palermo is 21h 50m, covering a distance of 673 km. The quickest bus can get you there in 21h 35m and is operated by FlixBus.
Which bus companies service the Pisa to Palermo route?
Several major bus companies operate on this route with 2 buses available per day.
What are the earliest and latest departure times for the bus from Pisa to Palermo?
The earliest bus departs from Pisa to Palermo at 6:05am. And the latest bus departs at 5:25pm.
What are the CO₂ emissions for the bus trip from Pisa to Palermo?
A bus trip from Pisa to Palermo generates an estimated 16.812025000000002 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Pisa to Palermo was searched and found on Jun 2, 2026 with a price of $133To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Pisa to Palermo, as early as possible.
