Find coaches from Pisa to Palermo

Find affordable coach tickets from Pisa to Palermo with flexible options. Book your journey now

Join 75M+ travellers booking 2M+ routes across 85+ countries.
Enjoy our 24/7 customer service to assist you at every stage.
Cancel anytime and receive a 100% refund, no reason needed.
Wed14 May
Today15 May
Tomorrow16 May
Sat17 May
Sun18 May
Mon19 May
from US$43
Tue20 May
Wed21 May

Cheap buses leaving Monday

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: 19 May at
    Departure city: Pisa
    Departure location: Parcheggio Via Pietransantina
    Arrival time: 20 May at
    Destination city: Palermo
    Destination location: Terminal Bus Palermo
    Operated by: Flixbus Flixbus
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: 19 May at
    Departure city: Pisa
    Departure location: Parcheggio Via Pietransantina
    Arrival time: 20 May at
    Destination city: Palermo
    Destination location: Terminal Bus Palermo
    Operated by: Flixbus Flixbus
    Vehicle: BusDuration:
  • Departure time: 19 May at
    Departure city: Pisa
    Departure location: Parcheggio Via Pietransantina
    Arrival time: 20 May at
    Destination city: Palermo
    Destination location: Terminal Bus Palermo
    Operated by: Flixbus Flixbus
    Vehicle: BusDuration:
  • Departure time: 19 May at
    Departure city: Pisa
    Departure location: park Aurelia
    Arrival time: 20 May at
    Destination city: Palermo
    Destination location: Terminal Bus Palermo
    Operated by: Flixbus Flixbus
    Vehicle: BusDuration:

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Compare 2 ways to travel from Pisa to Palermo

Average priceUS$48 - US$187Average duration21h 35m
17kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Carpool
Average priceUS$102 - US$102Average duration13h
28kg CO₂e4 out of 5 stars
Fastest
busbud logoBusbud recommends carpooling from Pisa to Palermo

Among the sustainable travel choices, the carpool stands out as a good way to reach Palermo. The journey takes about 13 hours and with fares starting at just US$102, it presents an excellent value for a comfortable ride.

2carpool per day
13hAverage duration
US$102Cheapest ticket
28kgCO₂ emissions

Bus Pisa to Palermo: Trip Overview

Average ticket priceUS$98
Average bus trip duration21h 35m
Number of daily buses3
Earliest bus departure05:45
Distance416 miles
Latest bus departure17:25

Pisa to Palermo Bus

Busbud helps you find a bus from Pisa to Palermo. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

Bus service from Pisa to Palermo will be provided by the most trusted bus companies.

From cheap bus tickets to more luxurious buses travelling from Pisa to Palermo, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Pisa - Palermo

  1. How much is coach from Pisa to Palermo?

    The price for a coach ticket from Pisa to Palermo starts at US$48, though the average is US$98. These prices can change depending on factors like the date, the class and the coach company you choose. Keep in mind that booking tickets on the day of travel might result in higher prices.

  2. How long does the coach from Pisa to Palermo take?

    The average duration for a trip from Pisa to Palermo by coach is around 21h 35m. The quickest coach journey typically takes 20h 55m. However, please keep in mind that your specific travel time may vary due to the prevailing traffic conditions along the route.

  3. At what time does the first coach from Pisa to Palermo leave?

    The first departure to Palermo is at 05:45. Keep in mind that departure times might change on weekends and holidays.

  4. What's the distance between Pisa and Palermo by coach?

    The distance between Pisa and Palermo by coach is approximately 417 miles (672 km).

  5. How can I travel from Pisa to Palermo avoiding air travel?

    You have the option to select the coach for your journey on this route. The coach ensures a pleasant travel experience, granting you the opportunity to appreciate the scenery as you make your way to your final stop. You might also find carpooling options to travel between the two cities.

  6. Can I catch a night coach from Pisa to Palermo?

    Yes, you can find buses leaving until 17:25 and arriving the next day. Remember to bring along some essentials like a snuggly blanket and a few treats for a comfortable trip.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
13/05
No data
14/05
No data
Today
No data
16/05
No data
17/05
No data
18/05
No data
19/05
US$44
20/05
No data
busbud logoThe cheapest trip from Pisa to Palermo was searched and found on 19 May 2025 with a price of US$44

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Pisa to Palermo as early as possible.

You can expect to pay from US$44 to US$54 for a bus ticket from Pisa to Palermo based on the last 2 days. You can expect to find the cheapest price for the trip at US$44, which is on 2025-05-19.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Pisa and Palermo!

Much more than a mere vehicle taking you from Pisa to Palermo, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Pisa to Palermo that are otherwise impossible to come by with a plane.

Make a music playlist for your bus ride from Pisa to Palermo, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

What's the cheapest way to go from Pisa to Palermo?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Pisa by bus?

Bus from Pisa to Palermo

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud makes bus travel easy. We help travellers find a bus, plot routes, and book intercity bus tickets all over the world. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

People from around the world trust Busbud

Popular Buses Connecting Pisa

Buses Leaving from Pisa

Buses Going to Pisa

Popular Buses Connecting Palermo

Buses Leaving from Palermo

Buses Going to Palermo