Bus from Rome to Prague: Tickets & Schedules

Next bus departures

Next departures for Rome to Prague on February 26
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Flixbus Bus
Rome Anagnina
PRG AirportCheapest
Flixbus Bus
Rome Anagnina
Prague (Main Railway Station)Fastest
Flixbus Bus
Aeroporto Ciampino Airport (CIA)
PRG AirportNo tags
Flixbus Bus
Aeroporto Ciampino Airport (CIA)
PRG AirportNo tags
Flixbus Bus
Rome Tiburtina Bus Station
PRG AirportNo tags

Last refresh of the prices: Yesterday at 1:10 AM CET.

Compare 2 ways to go from Rome to Prague

We recommend carpooling

Among the sustainable travel choices, the Carpool stands out as a good way to reach Prague. The journey takes about 14 hours, and with fares starting at just $89, it presents an excellent value for a comfortable ride.

1carpool per day
14hAverage Duration
924 kmDistance
39kgCO₂ emissions
Average Price$71 - $351Average Duration1d
23kg CO₂e
Carpool
Average Price$89 - $105Average Duration14h
39kg CO₂e

Frequently asked questions about travelling from Rome to Prague by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

  1. How much is the bus ticket from Rome to Prague?

    The cheapest bus tickets from Rome to Prague start from $71. The average price for this route is around $153. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

  2. How long is the bus ride from Rome to Prague?

    The average bus travel time from Rome to Prague is 1d , covering a distance of 932 km. The quickest bus can get you there in 19h 55m and is operated by FlixBus.

  3. Which bus companies service the Rome to Prague route?

    Several major bus companies operate on this route with 39 buses available per day, including services from FlixBus, RegioJet.

  4. What are the earliest and latest departure times for the bus from Rome to Prague?

    The earliest bus departs from Rome to Prague at 1:05am. And the latest bus departs at 11:50pm.

  5. What are the CO₂ emissions for the bus trip from Rome to Prague?

    A bus trip from Rome to Prague generates an estimated 23 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.

  6. What is the best bus company from Rome to Prague?

    According to Busbud customers, the highest-rated bus company on this route is RegioJet, with an average rating of 4.1 out of 5 stars based on 1069 reviews.

  7. Which bus company has the best Wi-Fi from Rome to Prague?

    Based on Busbud reviews, the bus company RegioJet has the highest Wi-Fi rating with a score of 3.8.

  8. Which bus company has the best on-time performance from Rome to Prague?

    According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 4.0 out of 5 stars.

  9. Which bus company has the cleanest buses from Rome to Prague?

    According to Busbud traveller reviews, the bus company with the cleanest buses on this route is RegioJet, with a cleanliness rating of 4.4 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
02-23
$118
02-24
No data
Today
$109
02-26
$120
02-27
$110
02-28
$107
03-01
No data
03-02
No data
busbud logoThe cheapest trip from Rome to Prague was searched and found on Feb 28, 2026 with a price of $107

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Rome to Prague, as early as possible.

You can expect to pay from $107 to $244 for a bus ticket from Rome to Prague based on the last 2 days. You can expect to find the cheapest price for the trip at $107 which is on 2026-02-28.

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