Bus Tickets from Rome to Prague

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TodayMay 12
from US$90
TomorrowMay 13
WedMay 14
from US$61
ThuMay 15
FriMay 16
SatMay 17
SunMay 18
MonMay 19

Cheap buses leaving Wednesday

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: May 14 at
    Departure city: Rome
    Departure location: Rome Anagnina
    Arrival time: May 15 at
    Destination city: Prague
    Destination location: PRG Airport
    Operated by: Flixbus Flixbus
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: May 14 at
    Departure city: Rome
    Departure location: Rome Tiburtina Bus Station
    Arrival time: May 15 at
    Destination city: Prague
    Destination location: Florenc
    Operated by: RegioJetRegioJet
    Vehicle: BusDuration:
  • Departure time: May 14 at
    Departure city: Rome
    Departure location: Rome Tiburtina Bus Station
    Arrival time: May 15 at
    Destination city: Prague
    Destination location: Florenc
    Operated by: RegioJetRegioJet
    Vehicle: BusDuration:
  • Departure time: May 14 at
    Departure city: Rome
    Departure location: Aeroporto Ciampino Airport (CIA)
    Arrival time: May 16 at
    Destination city: Prague
    Destination location: PRG Airport
    Operated by: Flixbus Flixbus
    Vehicle: BusDuration:
  • Departure time: May 14 at
    Departure city: Rome
    Departure location: Rome Tiburtina Bus Station
    Arrival time: May 15 at
    Destination city: Prague
    Destination location: PRG Airport
    Operated by: Flixbus Flixbus
    Vehicle: BusDuration:

Last refresh of the prices: Last Saturday at 11:45 PM CEST.

Prices and availability are subject to change.

Accepted payments

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  • China Union Pay
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Compare 2 ways to go from Rome to Prague

Bus
Average PriceUS$50 - US$338Average Duration1d
23kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Carpool
Average PriceUS$77 - US$77Average Duration14h 10m
39kg CO₂e4 out of 5 stars
Fastest
busbud logoBusbud recommends carpooling from Rome to Prague

Among the sustainable travel choices, the carpool stands out as a good way to reach Prague. The journey takes about 14 hours 10 minutes, and with fares starting at just US$77, it presents an excellent value for a comfortable ride.

1carpool per day
14h 10mAverage Duration
US$77Cheapest ticket
39kgCO₂ emissions

Bus Rome to Prague: Trip Overview

Average Ticket PriceUS$128
Average Bus Trip Duration1d
Number of daily buses54
Earliest bus departure1:05am
Distance938 km
Latest bus departure11:40pm

Rome to Prague Bus

With Busbud, comparing and booking tickets for a bus from Rome to Prague is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make it our job to connect you with the most dependable bus companies that cover bus service from Rome to Prague.

From cheap bus tickets to more luxurious buses travelling from Rome to Prague, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Rome - Prague

  1. How long does it take to get to Prague from Rome by bus?

    The trip from Rome to Prague will take on average 1d. For the shortest travel time, select the fastest bus available, which will take you to Prague in about 19h 10m.

  2. What is the distance between Rome and Prague?

    It's about 925 km (573 miles) from Rome to Prague.

  3. What are the departure and arrival locations for buses traveling from Rome to Prague?

    Buses departing from Rome Tiburtina Bus Station in Rome will take you to PRG Airport in Prague.

  4. What is the cheapest way to travel from Rome to Prague?

    The least expensive option to go from Rome to Prague would be going by bus. With a starting ticket price of US$50, this bus becomes your top pick for this journey.

  5. How much is the bus from Rome to Prague?

    You can expect to pay around US$128 for the bus ride from Rome to Prague.

  6. Is it possible to travel by overnight bus from Rome to Prague?

    Yes! If you're heading from Rome to Prague, you'll find buses departing until 11:40pm and arriving the next day.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
05-10
No data
05-11
US$112
Today
US$86
05-13
No data
05-14
US$58
05-15
No data
05-16
No data
05-17
No data
busbud logoThe cheapest trip from Rome to Prague was searched and found on May 14, 2025 with a price of US$58

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Rome to Prague, as early as possible.

You can expect to pay from US$58 to US$175 for a bus ticket from Rome to Prague based on the last 2 days. You can expect to find the cheapest price for the trip at US$58 which is on 2025-05-14.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Rome to Prague.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Rome to Prague.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Rome to Prague that are otherwise impossible to come by with a plane.

Tune out to the fine sounds of your best music playlist on your bus trip from Rome to Prague while indulging in miles on end of beautiful scenic views.

Did you know?

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Will you be returning to Rome by bus?

Bus from Rome to Prague

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Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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