How much is the bus ticket from Rome to Prague?

The cheapest bus tickets from Rome to Prague start from $58. The average price for this route is around $133. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the bus ride from Rome to Prague?

The average bus trip duration from Rome to Prague is 1d , covering a distance of 571 miles (921 km). The quickest bus can get you there in 20h 10m and is operated by RegioJet .

Which bus companies service the Rome to Prague route?

Several major bus companies operate on this route with 48 buses available per day, including services from FlixBus , RegioJet .

What is the earliest and latest departure time for the bus from Rome to Prague?

The earliest bus departs from Rome to Prague at 1:00am. And the latest bus departs at 11:50pm.

What are the CO₂ emissions for the bus trip from Rome to Prague?

A bus trip from Rome to Prague generates an estimated 23 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

What is the best bus company from Rome to Prague?

According to Busbud customers, the highest-rated bus company on this route is RegioJet , with an average rating of 4.1 out of 5 stars based on 1057 reviews.

Which bus company has the best Wi-Fi from Rome to Prague?

Based on reviews on Busbud, the bus company RegioJet has the best Wi-Fi rating with a score of 3.8.

Which bus company has the most timely service from Rome to Prague?

According to Busbud traveller reviews, the most timely bus company on this route is RegioJet , with a punctuality rating of 3.9 out of 5 stars.

Which bus company has the cleanest buses from Rome to Prague?

According to Busbud traveller reviews, the bus company with the cleanest buses on this route is RegioJet , with a cleanliness rating of 4.3 out of 5 stars.

Bus Rome to Prague from $67 | Refundable Tickets

Next bus departures

Next departures for Rome to Prague on November 28
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	9:00pm	Rome Tiburtina Bus Station	23h 15m	8:15pm	PRG Airport	Cheapest
Bus	1:05pm	Rome Anagnina	20h 20m	9:25am	Prague (Central Bus Station Florenc)	Fastest
Bus	10:45am	Aeroporto Ciampino Airport (CIA)	1d 3h	1:45pm	PRG Airport	No tags
Bus	11:10pm	Aeroporto Ciampino Airport (CIA)	1d 8h	7:15am	PRG Airport	No tags
Bus	12:20pm	Rome Tiburtina Bus Station	1d 1h	1:45pm	PRG Airport	No tags

Last refresh of the prices: Yesterday at 8:44 PM CET.

Compare 2 ways to go from Rome to Prague

We recommend carpooling

Among the sustainable travel choices, the carpool stands out as the good way to reach Prague. The journey takes about 14 hours and with fares starting at just $64, it presents an excellent value for a comfortable ride.

1carpool per day

14hAverage Duration

573 milesDistance

39kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$58 - $245	Average Duration1d	CO₂ emissions 23kg CO₂e
Carpool	Average Price$64 - $75	Average Duration14h	CO₂ emissions 39kg CO₂e

Where are the popular stops in Rome and Prague?

Stops in Rome

A
Rome Tiburtina Bus Station
Largo Guido Mazzoni, 3, 00162 Roma, Italy
Visit page
B
Rome Ciampino Airport
Visit page
C
Rome Fiumicino Airport
Visit page
D
Castro Pretorio
Viale Castro Pretorio 76, 00185 Roma, Italy
E
Roma
F
Anagnina
Via Vincenzo Giudice, 00173 Roma RM, Italy

Stops in Prague

A
Zličín
Drahoňovského, 163 00 Praha 17, Czech Republic
B
PRG Airport
Aviatická, 161 08, Praha 6, Czechia
Visit page
C
Tomíčkova
Tomíčkova 2234, Chodov, 148 00 Praha-Praha 11, Czechia
Visit page
D
Černý Most
Chlumecká, 198 00 Praha 20, Czech Republic
Visit page
E
Florenc
Křižíkova 2b, Nové Město, 186 00 Praha-Praha 8, Czech Republic
Visit page
F
Hlavní nádraží
300/8 Wilsonova, 110 00 Praha, Czechia
Visit page

Compare bus companies

FlixBus

3.5/511,464 reviews

Staff4.2

Timeliness3.9

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

RegioJet

4/51,057 reviews

Staff4.5

Timeliness3.9

Cleanliness4.4

Wifi3.8

CZ bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Rede Expressos, Trenitalia

Frequently asked questions about traveling from Rome to Prague by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from Rome to Prague?
The cheapest bus tickets from Rome to Prague start from $58. The average price for this route is around $133. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Rome to Prague?
The average bus trip duration from Rome to Prague is 1d , covering a distance of 571 miles (921 km). The quickest bus can get you there in 20h 10m and is operated by RegioJet.
Which bus companies service the Rome to Prague route?
Several major bus companies operate on this route with 48 buses available per day, including services from FlixBus, RegioJet.
What is the earliest and latest departure time for the bus from Rome to Prague?
The earliest bus departs from Rome to Prague at 1:00am. And the latest bus departs at 11:50pm.
What are the CO₂ emissions for the bus trip from Rome to Prague?
A bus trip from Rome to Prague generates an estimated 23 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Rome to Prague?
According to Busbud customers, the highest-rated bus company on this route is RegioJet, with an average rating of 4.1 out of 5 stars based on 1057 reviews.
Which bus company has the best Wi-Fi from Rome to Prague?
Based on reviews on Busbud, the bus company RegioJet has the best Wi-Fi rating with a score of 3.8.
Which bus company has the most timely service from Rome to Prague?
According to Busbud traveller reviews, the most timely bus company on this route is RegioJet, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Rome to Prague?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is RegioJet, with a cleanliness rating of 4.3 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11/26

$76

11/27

$100

Today

$96

11/29

No data

11/30

No data

12/01

No data

12/02

No data

12/03

$76

The cheapest trip from Rome to Prague was searched and found on Nov 26, 2025 with a price of $76

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Rome to Prague, as early as possible.

You can expect to pay from $76 to $232 for a bus ticket from Rome to Prague based on the last 2 days. You can expect to find the cheapest price for the trip at $76 which is on 2025-12-03.