Find coaches from Rome to Prague

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Today18 May
from US$64
Tomorrow19 May
Tue20 May
Wed21 May
from US$58
Thu22 May
Fri23 May
Sat24 May
Sun25 May

Cheap buses leaving Wednesday

One passenger / one way

  • This trip is recommended because it is the: Cheapest + Fastest
    Departure time: 21 May at
    Departure city: Rome
    Departure location: Rome Tiburtina Bus Station
    Arrival time: 22 May at
    Destination city: Prague
    Destination location: Florenc
    Operated by: RegioJetRegioJet
    Vehicle: BusDuration:

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Compare 2 ways to travel from Rome to Prague

Bus
Average priceUS$50 - US$338Average duration1d
23kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Carpool
Average priceUS$77 - US$77Average duration14h 10m
39kg CO₂e4 out of 5 stars
Fastest
busbud logoBusbud recommends carpooling from Rome to Prague

Among the sustainable travel choices, the carpool stands out as a good way to reach Prague. The journey takes about 14 hours 10 minutes and with fares starting at just US$77, it presents an excellent value for a comfortable ride.

1carpool per day
14h 10mAverage duration
US$77Cheapest ticket
39kgCO₂ emissions

Bus Rome to Prague: Trip Overview

Average ticket priceUS$125
Average bus trip duration1d
Number of daily buses54
Earliest bus departure01:05
Distance575 miles
Latest bus departure23:35

Rome to Prague Bus

With Busbud, comparing and booking tickets for a bus from Rome to Prague is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make it our job to connect you with the most dependable bus companies that cover bus service from Rome to Prague.

From cheap bus tickets to more luxurious buses travelling from Rome to Prague, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Rome - Prague

  1. How much does it cost to go to Prague by bus?

    The prices typically range from US$50 to US$338 on this trip, with the average ticket costing US$125. The actual price may differ based on factors like the time you plan to travel, the day of the week, and the coach service provider you select. Compare the prices and amenities offered by each company on Busbud and find the best deals and offers.

  2. How long is a coach from Rome to Prague?

    The coach journey between Rome and Prague lasts about 1d. The quickest coach journey typically takes 19h 10m. Please be aware that the time it takes for your journey may vary depending on the traffic conditions along the route.

  3. At what time is the first coach from Rome to Prague?

    The first coach to Prague from Rome departs at 01:05. Keep in mind that departure times might change on weekends and holidays.

  4. What's the distance between Rome and Prague by coach?

    The journey from Rome to Prague by coach covers an approximate distance of 573 miles (925 km).

  5. What is the best way to go from Rome to Prague without flying?

    You can choose the coach to travel this route. Choosing the coach guarantees a comfortable and sustainable travel experience, allowing you to admire the views on your way to your destination. You might also find carpooling options to travel between the two cities.

  6. Can I catch a night bus from Rome to Prague?

    Yes, you can find buses leaving until 23:35 and arriving the next day. Make sure to bring a snack and a blanket to keep yourself feeling comfortable during the night.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
16/05
No data
17/05
No data
Today
US$65
19/05
No data
20/05
No data
21/05
US$58
22/05
No data
23/05
US$58
busbud logoThe cheapest trip from Rome to Prague was searched and found on 21 May 2025 with a price of US$58

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Rome to Prague as early as possible.

You can expect to pay from US$58 to US$118 for a bus ticket from Rome to Prague based on the last 2 days. You can expect to find the cheapest price for the trip at US$58, which is on 2025-05-21.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Rome to Prague.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Rome to Prague.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Rome to Prague that are otherwise impossible to come by with a plane.

Tune out to the fine sounds of your best music playlist on your bus trip from Rome to Prague while indulging in miles on end of beautiful scenic views.

Did you know?

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Will you be returning to Rome by bus?

Bus from Rome to Prague

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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