- San Diego to St. Louis buses
Next departures
Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound Lines, Inc. | Downtown SD (Seaport) | Gateway Station | Cheapest | |||||
FlixBus + Greyhound Lines, Inc. | UCSD Health La Jolla Station | Gateway Station | Fastest | |||||
FlixBus + Greyhound Lines, Inc. | San Diego (Old Town-FlixBus) | Gateway Station | No tags | |||||
![]() | Greyhound Bus Stop | Gateway Station | No tags | |||||
FlixBus + Greyhound Lines, Inc. | San Diego (Old Town-FlixBus) | Gateway Station | No tags |
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Bus San Diego, CA, US to St. Louis: Trip Overview
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San Diego to St. Louis Bus
Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from San Diego to St. Louis.
We make sure you can find a bus service from San Diego to St. Louis from the most reliable bus companies operating this trip.
From cheap bus tickets to more luxurious buses travelling from San Diego to St. Louis, we offer a wide range of bus services to best suit your needs depending on how much your budget is.
Where are the popular stops in San Diego and St. Louis?
Frequently asked questions on the trip San Diego, CA, US - St. Louis
How far is San Diego from St. Louis?
The distance covered from San Diego to St. Louis is 2516 km (1560 miles).
What are the departure and arrival locations for buses traveling from San Diego to St. Louis?
Buses traveling this route start their trip at Mission Valley Sheraton, in San Diego, and end it at Gateway Station, in St. Louis.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Diego, CA, US to St. Louis, as early as possible.
You can expect to pay from US$207 to US$377 for a bus ticket from San Diego, CA, US to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at US$207 which is on 2025-10-15.
About Bus Travel
Bus Travel Tips
If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from San Diego to St. Louis but it'll also be endearing to native speakers who will surely appreciate your effort.
Start sightseeing the minute your bus leaves the station. If you're on the night bus from San Diego to St. Louis, get comfy and count the stars.
Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from San Diego to St. Louis that are otherwise impossible to come by with a plane.
Tune out to the fine sounds of your best music playlist on your bus trip from San Diego to St. Louis while indulging in miles on end of beautiful scenic views.
Did you know?
The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!
Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.
One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.
Top travelled bus routes
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Popular Buses Connecting San Diego
Buses Leaving from San Diego
- Bus from San Diego to San Ysidro
- Bus San Diego - Lafayette
- San Diego - Lafayette
- Bus from San Diego to San Marcos
- Bus San Diego - San Francisco
- San Diego - Las Vegas
- Bus from San Diego to Los Angeles
- Bus San Diego - Palm Springs
- San Diego - Las Vegas
- Bus from San Diego to Phoenix
- Bus San Diego - Temecula
- San Diego - Anaheim
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- Bus San Diego - Calexico
- San Diego - Napa
Buses Going to San Diego
- Bus from Manchester to San Diego
- Bus Santa Fe - San Diego
- San Marcos - San Diego
- Bus from Grants to San Diego
- Bus Spring Hill - San Diego
- Seattle - San Diego
- Bus from Palm Springs to San Diego
- Bus Las Vegas - San Diego
- Yuma - San Diego
- Bus from Anaheim to San Diego
- Bus Willcox - San Diego
- Bellingham - San Diego
- Bus from Phoenix to San Diego
- Bus San Francisco - San Diego
- Ontario - San Diego
Popular Buses Connecting St. Louis
Buses Leaving from St. Louis
- Bus from St. Louis to New Orleans
- Bus St. Louis - Kansas City
- St. Louis - Kansas City
- Bus from St. Louis to Austin
- Bus St. Louis - Buffalo
- St. Louis - Nashville
- Bus from St. Louis to Indianapolis
- Bus St. Louis - Columbia
- St. Louis - Chicago
- Bus from St. Louis to Champaign
- Bus St. Louis - Houston
- St. Louis - Murfreesboro
- Bus from St. Louis to Gary
- Bus St. Louis - Rockford
- St. Louis - Lawrence
Buses Going to St. Louis
- Bus from New Orleans to St. Louis
- Bus Indianapolis - St. Louis
- Manchester - St. Louis
- Bus from Manchester to St. Louis
- Bus Atlanta - St. Louis
- Detroit - St. Louis
- Bus from Chicago to St. Louis
- Bus Cheyenne - St. Louis
- Lafayette - St. Louis
- Bus from Springfield to St. Louis
- Bus Columbia - St. Louis
- Pasco - St. Louis
- Bus from Buffalo to St. Louis
- Bus Sandusky - St. Louis
- Champaign - St. Louis
Popular routes in this country
- Bus from Washington to New York City
- Bus Boston - New York City
- New York City - Boston
- Bus from Buffalo to New York City
- Bus Philadelphia - New York City
- Niagara Falls - New York City
- Bus from Baltimore to New York City
- Bus Baton Rouge - New Orleans
- Albany - New York City
- Bus from Detroit to Chicago
- Bus Atlanta - Savannah
- Las Vegas - Los Angeles
- Bus from Los Angeles to San Diego
- Bus New York City - Burlington
- Miami - Orlando