Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Terminal San Felipe | La Serena (Bus terminal La Serena) | No tags | |||||
| Terminal San Felipe | La Serena (Bus terminal La Serena) | No tags | |||||
| Terminal San Felipe | La Serena (Bus terminal La Serena) | No tags | |||||
| Terminal San Felipe | La Serena (Bus terminal La Serena) | No tags | |||||
| Terminal San Felipe | La Serena (Bus terminal La Serena) | No tags |
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Bus San Felipe, CL to La Serena, CL: Trip Overview
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Based on 10828 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. FlixBus ticket prices on this trip start at US$14
San Felipe to La Serena Bus
Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from San Felipe to La Serena.
We make it our job to connect you with the most dependable bus companies that cover bus service from San Felipe to La Serena.
Whether it is cheap bus tickets or more luxurious buses going to La Serena from San Felipe, we help you find what you're looking for based on how much of a budget you have.
Where are the popular stops in San Felipe and La Serena?
Frequently asked questions on the trip San Felipe, CL - La Serena, CL
What is the travel distance from San Felipe to La Serena?
The distance between San Felipe and La Serena is approximately 321 km (199 miles).
What are the departure and arrival locations for buses traveling from San Felipe to La Serena?
Buses departing from Terminal de Autobuses de San Felipe in San Felipe will take you to Terminal de Buses La Serena in La Serena.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from San Felipe, CL to La Serena, CL was searched and found on Oct 8, 2025 with a price of US$13To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Felipe, CL to La Serena, CL, as early as possible.
About Bus Travel
Bus Travel Tips
If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from San Felipe to La Serena but it'll also be endearing to native speakers who will surely appreciate your effort.
From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from San Felipe to La Serena.
Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from San Felipe to La Serena.
Tune out to the fine sounds of your best music playlist on your bus trip from San Felipe to La Serena while indulging in miles on end of beautiful scenic views.
Did you know?
The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.
The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.
The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!
Top travelled bus routes
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Popular Buses Connecting San Felipe
Buses Leaving from San Felipe
Buses Going to San Felipe
Popular Buses Connecting La Serena
Buses Leaving from La Serena
- Bus from La Serena to Coquimbo
- Bus La Serena - Santiago
- La Serena - Temuco
- Bus from La Serena to Ovalle
- Bus La Serena - Vallenar
- La Serena - Antofagasta
- Bus from La Serena to Caldera
- Bus La Serena - Valparaiso
- La Serena - Los Andes
- Bus from La Serena to Copiapo
- Bus La Serena - Vicuña
- La Serena - Calama
- Bus from La Serena to Baquedano
- Bus La Serena - Tocopilla
- La Serena - Los Vilos
Buses Going to La Serena
- Bus from Santiago to La Serena
- Bus Ovalle - La Serena
- Calama - La Serena
- Bus from Copiapo to La Serena
- Bus Temuco - La Serena
- Valparaiso - La Serena
- Bus from Caldera to La Serena
- Bus Diego de Almagro - La Serena
- Antofagasta - La Serena
- Bus from Los Vilos to La Serena
- Bus Baquedano - La Serena
- Quillota - La Serena
- Bus from Pullalli to La Serena
- Bus Coquimbo - La Serena
- La Calera - La Serena
Popular routes in this country
- Bus from Castro to Ancud
- Bus Puerto Varas - Castro
- Santiago - Valparaiso
- Bus from Santiago to Pucon
- Bus Calama - Santiago
- Santiago - Vina del Mar
- Bus from Puerto Montt to Pucon
- Bus Puerto Natales - Estancia Pudeto
- Calama - Arica Province
- Bus from Temuco to Pucon
- Bus Ancud - Puerto Montt
- Valdivia - Santiago
- Bus from Arica Province to Calama
- Bus Puerto Montt - Santiago
- San Antonio - Santiago