Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | San Ysidro Bus terminal | Las Cruces (Mesilla Valley Intermodal Transit Terminal) | Cheapest | ||||
 | Bus | San Ysidro Greyhound Bus Station | Las Cruces Bus Station | Fastest | ||||
FlixBus + Greyhound Lines, Inc. | Bus | San Ysidro Bus terminal | Las Cruces (Mesilla Valley Intermodal Transit Terminal) | No tags | ||||
| Bus | San Ysidro Greyhound Bus Station | Las Cruces Bus Station | No tags | ||||
FlixBus + Greyhound Lines, Inc. | Bus | San Ysidro Bus terminal | Las Cruces (Mesilla Valley Intermodal Transit Terminal) | No tags |
Last refresh of the prices: Last Friday at 7:06 AM PST.
Get from San Ysidro to Las Cruces
The journey takes about 19 hours, and with fares starting at just $197, it presents an excellent value for a comfortable ride.
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Frequently asked questions about travelling from San Ysidro, CA to Las Cruces, US by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from San Ysidro to Las Cruces?
The cheapest bus tickets from San Ysidro to Las Cruces start from $197. The average price for this route is around $201. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from San Ysidro to Las Cruces?
The average bus travel time from San Ysidro to Las Cruces is 19h, covering a distance of 961 km. The quickest bus can get you there in 15h 40m and is operated by Los Limousines.
Which bus companies service the San Ysidro to Las Cruces route?
Several major bus companies operate on this route with 12 buses available per day, including services from Los Limousines, Greyhound.
What are the earliest and latest departure times for the bus from San Ysidro to Las Cruces?
The earliest bus departs from San Ysidro to Las Cruces at 6:55am. And the latest bus departs at 7:00pm.
What are the CO₂ emissions for the bus trip from San Ysidro to Las Cruces?
A bus trip from San Ysidro to Las Cruces generates an estimated 24 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from San Ysidro to Las Cruces?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87500 reviews.
Which bus company has the best Wi-Fi from San Ysidro to Las Cruces?
Based on Busbud reviews, the bus company Los Limousines has the highest Wi-Fi rating with a score of 2.7.
Which bus company has the best on-time performance from San Ysidro to Las Cruces?
According to Busbud traveller reviews, the most punctual bus company on this route is Greyhound, with a punctuality rating of 2.9 out of 5 stars.
Which bus company has the cleanest buses from San Ysidro to Las Cruces?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Los Limousines, with a cleanliness rating of 3.9 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from San Ysidro, CA to Las Cruces, US was searched and found on Jan 21, 2026 with a price of $153To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Ysidro, CA to Las Cruces, US, as early as possible.
You can expect to pay from $153 to $284 for a bus ticket from San Ysidro, CA to Las Cruces, US based on the last 2 days. You can expect to find the cheapest price for the trip at $153 which is on 2026-01-21.
Usually Los Limousines will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
