Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | San Ysidro Bus terminal | Bus Station | CheapestFastest |
Last refresh of the prices: Last Tuesday at 5:07 AM PST.
Get from San Ysidro to Myrtle Beach
The journey takes about 2 days, 17 hours 50 minutes, and with fares starting at just $324, it presents an excellent value for a comfortable ride.
Where are the popular stops in San Ysidro and Myrtle Beach?
Compare bus companies
Based on 87490 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. Greyhound ticket prices on this trip start at $354
Frequently asked questions about travelling from San Ysidro, CA to Myrtle Beach by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from San Ysidro to Myrtle Beach?
The cheapest bus tickets from San Ysidro to Myrtle Beach start from $324. The average price for this route is around $354. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from San Ysidro to Myrtle Beach?
The average bus travel time from San Ysidro to Myrtle Beach is 2d 17h, covering a distance of 3535 km. The quickest bus can get you there in 2d 17h and is operated by Greyhound.
Which bus companies service the San Ysidro to Myrtle Beach route?
Several major bus companies operate on this route with 1 buses available per day.
What are the earliest and latest departure times for the bus from San Ysidro to Myrtle Beach?
The earliest bus departs from San Ysidro to Myrtle Beach at 1:15pm. And the latest bus departs at 7:00pm.
What are the CO₂ emissions for the bus trip from San Ysidro to Myrtle Beach?
A bus trip from San Ysidro to Myrtle Beach generates an estimated 88 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from San Ysidro, CA to Myrtle Beach was searched and found on Jan 8, 2026 with a price of $318To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Ysidro, CA to Myrtle Beach, as early as possible.
